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Major recanalization occurs more often in young patients after unruptured aneurysm coil embolization

  • Clinical Article - Vascular
  • Published:
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Abstract

Background

The recanalization rate after coil embolization of unruptured aneurysms was compared between young and old age groups.

Methods

From May 2003 to December 2010, 636 patients with 715 saccular unruptured intracranial aneurysms (UIA) underwent endovascular coiling and were followed for at least 6 months. For comparative analysis, patients were categorized into two groups according to age 40: 42 patients with 46 aneurysms who were 40 years or younger (young age group) and 594 patients with 669 aneurysms who were older than 40 years (old age group). Angiographic and clinical outcomes including recanalization rates were compared.

Results

Angiographically, class 1 or 2 occlusion according to the Raymond–Roy Occlusion Classification system was achieved in 89.2 % of the patients (91.3 % in the young age group and 89.1 % in the old age group, p = 0.74). Procedure-related complication rate was 2.2 % and 3.4 % in the young and the old age group (p = 0.16), respectively. The mean follow-up duration was 30.51 ± 18.59 months. Major recanalization occurred in seven aneurysms (15.2 %) in the young age group and in 44 aneurysms (6.6 %) in the old age group (p = 0.03). Retreatment was performed in seven patients (15.2 %) in the young age group and in 35 patients (5.2 %) in the old age group (p = 0.01).

Conclusions

The present study showed that the technical feasibility and safety of endovascular coiling for UIA did not differ between the two age groups. However, the major recanalization rate was higher in the young age group.

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Authors and Affiliations

  1. Department of Neurosurgery, Seoul National University Boramae Medical Center, Seoul, South Korea

    Young-Je Son

  2. Department of Neurosurgery, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, 463-707, Seongnam, Gyeonggido, South Korea

    O-Ki Kwon, Gyojun Hwang, Nam Mi Park, Chang Wan Oh & Jae Seung Bang

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  1. Young-Je Son
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  2. O-Ki Kwon
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  3. Gyojun Hwang
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  4. Nam Mi Park
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  5. Chang Wan Oh
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Correspondence to O-Ki Kwon.

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Funding

Seoul National University Bundang Hospital provided financial support in the form of research funding (grant no. 14-2014-002). The sponsor had no role in the design or conduct of this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speaker’s bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

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Son, YJ., Kwon, OK., Hwang, G. et al. Major recanalization occurs more often in young patients after unruptured aneurysm coil embolization. Acta Neurochir 158, 551–556 (2016). https://doi.org/10.1007/s00701-015-2668-1

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  • DOI: https://doi.org/10.1007/s00701-015-2668-1

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