Abstract
Tolosa-Hunt syndrome is a rare cause of painful ophthalmoplegia due to idiopathic chronic granulomatous inflammation in the cavernous sinus. Usually clinical manifestations are well controlled by corticosteroid therapy, but steroid dependency or resistance is common. We report a case of marked improvement of Tolosa-Hunt syndrome without symptom relapse after Gamma Knife radiosurgery in a patient with steroid intolerance.
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References
Chkhikvishvili T, Khevsuriani Sh O, Gegechkori MV, Abelashvili RI, Kurtishvili GG (1978) Diagnosis and treatment of the Tolosa-Hunt syndrome. Zh Nevropatol Psikhiatr Im S S Korsakova 78:204–206
Headache Classification Committee of the International Headache S (2013) The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 33:629–808
Hunt WE, Meagher JN, Lefever HE, Zeman W (1961) Painful opthalmoplegia. Its relation to indolent inflammation of the carvernous sinus. Neurology 11:56–62
Tolosa E (1954) Periarteritic lesions of the carotid siphon with the clinical features of a carotid infraclinoidal aneurysm. J Neurol Neurosurg Psychiatry 17:300–302
Foubert-Samier A, Sibon I, Maire JP, Tison F (2005) Long-term cure of Tolosa-Hunt syndrome after low-dose focal radiotherapy. Headache 45:389–391
Furukawa Y, Yamaguchi W, Ito K, Hamada T, Miyaji H, Tamamura H, Yamada M (2010) The efficacy of radiation monotherapy for Tolosa-Hunt syndrome. J Neurol 257:288–290
Larner JM, Malcom R, Miller JQ, Newman SA (1991) Tolosa-Hunt syndrome—a radiation responsive syndrome. Neuro-Ophthalmology 11:289–292
Mormont E, Laloux P, Vauthier J, Ossemann M (2000) Radiotherapy in a case of Tolosa-Hunt syndrome. Cephalalgia 20:931–933
Nasr YG, Boghen D, Vezina J (1987) Tolosa-Hunt syndrome with a prolonged course - successful treatment with radiotherapy. Neuro-Ophthalmology 7:57–60
Hannerz J (1992) Recurrent Tolosa-Hunt syndrome. Cephalalgia 12:45–51
Jain R, Sawhney S, Koul RL, Chand P (2008) Tolosa-Hunt syndrome: MRI appearances. J Med Imaging Radiat Oncol 52:447–451
Luchin EI, Minakova EI, Krymskii VA (1987) Effect of proton irradiation of Tolosa-Hunt syndrome. Med Radiol (Mosk) 32:55–57
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Lee, JM., Park, JS. & Koh, EJ. Gamma Knife radiosurgery in steroid-intolerant Tolosa-Hunt syndrome: case report. Acta Neurochir 158, 143–145 (2016). https://doi.org/10.1007/s00701-015-2648-5
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DOI: https://doi.org/10.1007/s00701-015-2648-5