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An amino-functionalized zirconium-based metal-organic framework of type UiO-66-NH2 covered with a molecularly imprinted polymer as a sorbent for the extraction of aflatoxins AFB1, AFB2, AFG1 and AFG2 from grain

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Abstract

A surface imprinted polymer of type UiO-66-NH2@MIP was prepared by combining molecular imprinted polymers (MIPs) and an amino-functionalized zirconium-based metal-organic framework. Quercetin is used as the virtual template, UiO-66-NH2 acts as the carrier to which the monomer acrylamide can be copolymerized. The material was characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy. It was used as a sorbent in a solid-phase extraction column. The extraction conditions were optimized. The adsorption capacities for aflatoxins AFB1, AFB2, AFG1 and AFG2 by this SPE and by the commercial SPE were compared. The method was successfully applied to quantify the aflatoxins in grain. Figures of merit include (a) good linearity (range from 0.20–45 μg·kg−1) with R2 (range from 0.9986–0.9994), (b) low detection limits (90–130 ng·kg−1), (c) acceptable reproducibility (1.0–5.9%; for n = 6), and (d) relatively satisfactory recovery rates (74.3–98.6%). The new sorbent has good selectivity and reusability.

UiO-66-NH2@MIPs were synthesized with modified UIO-66-NH2 as core and quercetin as pseudo template. A cartridge was prepared with the polymers as the sorbent, and its performance was compared with different commercial SPE cartridges.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (grant numbers 21575034, 51502079, 21475119, 21775140), the Fundamental Research Funds for the Henan Provincial Colleges and Universities in Henan University of Technology (grant numbers 2017RCJH10).

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Authors and Affiliations

  1. School of Chemical Engineering and Environment, Henan University of Technology, Zhengzhou, 450001, People’s Republic of China

    Yutao Liang, Juan He, Zhipeng Huang, Yunxia Zhang, Huige Wang, Chaofan Rui, Yuanyuan Li & Liqin You

  2. Technology Center, Henan Cigarette Industrial Reconstituted Tobacco Sheet, Xuchang, 461000, People’s Republic of China

    Huayu Li

  3. College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, People’s Republic of China

    Kai Li & Shusheng Zhang

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  1. Yutao Liang
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  2. Juan He
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  10. Kai Li
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Correspondence to Juan He.

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Liang, Y., He, J., Huang, Z. et al. An amino-functionalized zirconium-based metal-organic framework of type UiO-66-NH2 covered with a molecularly imprinted polymer as a sorbent for the extraction of aflatoxins AFB1, AFB2, AFG1 and AFG2 from grain. Microchim Acta 187, 32 (2020). https://doi.org/10.1007/s00604-019-3959-7

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