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Carbon fibers coated with urchin-like copper sulfide for nonenzymatic voltammetric sensing of glucose

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Abstract

Urchin-like CuS was grown on xanthan gum-derived carbon nanofibers to obtain a sensor for enzyme-free electrochemical sensing of glucose. The unique nanostructure of the sensor provides a large specific surface, more electrocatalytically active sites, and high electrical conductivity. The voltammetric response to glucose, best measured at around 57 mV (vs. Ag/AgCl (E/V)) in 0.1 M NaOH solution, covers two linear ranges, one from 0.1–125 μM, another from 0.16 to 1.2 mM. The sensitivity is quite high (23.7 μA mM−1 cm−2), and the detection limit is low (19 nM at S/N = 3). The sensor has high selectivity against potentially interfering molecules such as fructose, appreciable operational stability, excellent durability, and good repeatability (with relative standard deviations of 2.3%). It was successfully applied to the determination of glucose in diluted serum samples.

Schematic representation of electrochemical detection of glucose based on the use of a screen printed carbon electrode (SPCE) modified with CuS and xanthan gum-derived carbon nanofibers (XGCNFs).

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Acknowledgements

This project was supported by the Ministry of Science and Technology (MOST 106-2113-M-027-003), Taiwan, ROC.

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Authors and Affiliations

  1. Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, Republic of China

    Murugan Keerthi, Bhuvanenthiran Mutharani & Shen-Ming Chen

  2. Institute of Organic and Polymeric Materials and Research and Development Center for Smart Textile Technology, National Taipei University of Technology, Taipei, Taiwan, Republic of China

    Palraj Ranganathan

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  1. Murugan Keerthi
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  2. Bhuvanenthiran Mutharani
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  3. Shen-Ming Chen
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  4. Palraj Ranganathan
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Correspondence to Shen-Ming Chen.

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Keerthi, M., Mutharani, B., Chen, SM. et al. Carbon fibers coated with urchin-like copper sulfide for nonenzymatic voltammetric sensing of glucose. Microchim Acta 186, 807 (2019). https://doi.org/10.1007/s00604-019-3915-6

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