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Surgical treatment of renal cell carcinoma with inferior vena cava tumor thrombus

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Abstract

Purpose

The present report discusses the indications of cardiopulmonary bypass (CPB) in open nephrectomy and surgical outcomes of conventional and minimally invasive surgical techniques for treating advanced renal cell carcinoma with inferior vena cava tumor thrombus.

Methods

The present study involved a comprehensive retrieval of pertinent literature from the most recent two decades.

Results

Comparisons between radical nephrectomy procedures in terms of open, laparoscopic and robotic-assisted surgeries revealed that open surgery had more blood loss, a longer operation time and higher mortality rates than laparoscopic and robotic-assisted surgeries. Furthermore, surgery with CPB was associated with more blood loss than non-CPB surgery. Rates of early and late deaths were much higher in patients with CPB than in those without CPB.

Conclusions

Different surgical techniques had different indications in terms of levels of inferior vena cava tumor thrombus. The laparoscopic, robotic-assisted, open surgical techniques and CPB with deep hypothermic circulatory arrest were indicated for Levels I, II, III and III–IV inferior vena cava tumor thrombus, respectively. Laparoscopic and robotic-assisted surgeries cause less trauma than open surgery but require more complicated equipments to support the procedure. CPB should be avoided in radical nephrectomy whenever possible. The increased application of laparoscopic and robotic techniques in the future is anticipated.

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Acknowledgements

I thank my colleague urologists Drs. Yin-Suo Wu and Yuan-Tian Lin for their kind support.

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  1. Department of Cardiothoracic Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, Fujian, People’s Republic of China

    Shi-Min Yuan

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Yuan, SM. Surgical treatment of renal cell carcinoma with inferior vena cava tumor thrombus. Surg Today 52, 1125–1133 (2022). https://doi.org/10.1007/s00595-021-02429-9

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