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Laparoscopic partial liver resection improves the short-term outcomes compared to open surgery for liver tumors in the posterosuperior segments

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Abstract

Purpose

The aim of this study was to compare the clinical outcomes between laparoscopic partial liver resection and open partial hepatectomy for tumors in the posterosuperior segments.

Methods

The clinical outcomes of patients who underwent either laparoscopic (n = 20) or open (n = 44) resection in segments 7/8 of the liver were initially evaluated. Because of disparities in the background characteristics, a case-matched study (1:1) was conducted. In addition, a comparative study of the patients who met the institutional criteria for laparoscopic partial hepatectomy was performed.

Results

In the case-matched study, the laparoscopic technique required a longer operation time (p = 0.001), but was associated with less intraoperative blood loss (p = 0.021), a lower incidence of major complications (p = 0.014), higher levels of serum albumin on postoperative days 3 and 7 (p = 0.031 and p = 0.035), and earlier discharge (p = 0.001) than open resection. The results of the latter study were similar to those of the case-matched analysis.

Conclusions

Laparoscopic partial hepatectomy was a feasible procedure for treating tumors in the posterosuperior segments without compromising oncological safety and yielded better short-term outcomes than open techniques. In addition, this study provides concrete selection criteria for laparoscopic partial hepatectomy for difficult lesions.

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Authors and Affiliations

  1. Department of Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan

    Takanori Morikawa, Masaharu Ishida, Tatsuyuki Takadate, Takeshi Aoki, Hideo Ohtsuka, Masamichi Mizuma, Hiroki Hayashi, Kei Nakagawa, Fuyuhiko Motoi, Takeshi Naitoh & Michiaki Unno

Authors
  1. Takanori Morikawa
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  2. Masaharu Ishida
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  3. Tatsuyuki Takadate
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  4. Takeshi Aoki
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  5. Hideo Ohtsuka
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  6. Masamichi Mizuma
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  7. Hiroki Hayashi
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  8. Kei Nakagawa
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  10. Takeshi Naitoh
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  11. Michiaki Unno
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Corresponding author

Correspondence to Takanori Morikawa.

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Conflict of interest

Takanori Morikawa and the co-authors have no conflicts of interest or financial ties to disclose in association with this study.

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Morikawa, T., Ishida, M., Takadate, T. et al. Laparoscopic partial liver resection improves the short-term outcomes compared to open surgery for liver tumors in the posterosuperior segments. Surg Today 49, 214–223 (2019). https://doi.org/10.1007/s00595-018-1719-7

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  • DOI: https://doi.org/10.1007/s00595-018-1719-7

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