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The results of allogenic cancellous bone graft in medial opening wedge high tibial osteotomy

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European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Purpose

There is no clear consensus regarding the optimal filling agent in the medial opening wedge high tibial osteotomy (MOWHTO). In this study, we evaluated the clinical and radiologic outcomes of MOWHTO with an allogeneic cancellous bone graft and TomoFix plate.

Methods

Medical profiles of 122 patients who underwent MOWHTO with cancellous bone graft from iliac crest were retrospectively reviewed. One hundred and two patients (120 knees) who met the study criteria were included in the analysis. The osteotomy site was fixed with a TomoFix plate. The mean age of the patients was 40.85 ± 22.15 years. The mean follow-up of the patients was 33.2 ± 29 months. The primary outcome measures were the union of osteotomy site and loss of correction that were investigated on postoperative radiographs. Secondary outcome measures were postoperative complications that were extracted from the patients' medical records.

Results

Union of the osteotomy site was observed in all patients within three months after the operation. Loss of correction at the osteotomy site occurred in two knees (1.7%), both of which underwent revision surgery. Three patients had non-infected prolonged wound drainage and underwent reoperation for allograft removal. Nine other complications were also recorded that did not require intervention, including superficial infection (n = 2), compartment syndrome (n = 1), deep vein thrombosis (n = 1), loss of knee flexion (n = 2), and transient pain at the site of the osteotomy (n = 3).

Conclusion

Allogenic cancellous bone graft provides efficient gap healing in MOWHTO and can be used as an effective alternative to the autogenous bone graft.

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References

  1. Matsumoto K, Ogawa H, Yoshioka H, Akiyama H (2020) Differences in patient-reported outcomes between medial opening-wedge high tibial osteotomy and total knee arthroplasty. J Orthop Surg 28(1):2309499019895636. https://doi.org/10.1177/2309499019895636

    Article  Google Scholar 

  2. Gomoll AH (2011) High tibial osteotomy for the treatment of unicompartmental knee osteoarthritis: a review of the literature, indications, and technique. Phys Sportsmed 39(3):45–54. https://doi.org/10.3810/psm.2011.09.1920

    Article  PubMed  Google Scholar 

  3. Noyes FR, Mayfield W, Barber-Westin SD, Albright JC, Heckmann TP (2006) Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function. Am J Sports Med 34(8):1262–1273. https://doi.org/10.1177/0363546505286144

    Article  PubMed  Google Scholar 

  4. Ahlmann E, Patzakis M, Roidis N, Shepherd L, Holtom P (2002) Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am 84(5):716–720. https://doi.org/10.2106/00004623-200205000-00003

    Article  PubMed  Google Scholar 

  5. Ren YM, Duan YH, Sun YB, Yang T, Hou WY, Zhu RS, Tian MQ (2020) Opening-wedge high tibial osteotomy using autograft versus allograft: a systematic review and meta-analysis. J Knee Surg 33(6):565–575. https://doi.org/10.1055/s-0039-1681065

    Article  PubMed  Google Scholar 

  6. Brouwer RW, Bierma-Zeinstra SM, van Raaij TM, Verhaar JA (2006) Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a puddu plate a one-year randomised, controlled study. J Bone Joint Surg Br 88(11):1454–1459. https://doi.org/10.1302/0301-620x.88b11.17743

    Article  CAS  PubMed  Google Scholar 

  7. Heary RF, Schlenk RP, Sacchieri TA, Barone D, Brotea C (2002) Persistent iliac crest donor site pain: independent outcome assessment. Neurosurgery 50(3):510–516. https://doi.org/10.1097/00006123-200203000-00015

    Article  PubMed  Google Scholar 

  8. Yacobucci GN, Cocking MR (2008) Union of medial opening-wedge high tibial osteotomy using a corticocancellous proximal tibial wedge allograft. Am J Sports Med 36(4):713–719. https://doi.org/10.1177/0363546507312646

    Article  PubMed  Google Scholar 

  9. Cho SW, Kim DH, Lee GC, Lee SH, Park SH (2013) Comparison between autogenous bone graft and allogenous cancellous bone graft in medial open wedge high tibial osteotomy with 2-year follow-up. Knee Surg Relat Res 25(3):117–125. https://doi.org/10.5792/ksrr.2013.25.3.117

    Article  PubMed  PubMed Central  Google Scholar 

  10. Whelan DB, Bhandari M, McKee MD, Guyatt GH, Kreder HJ, Stephen D, Schemitsch EH (2002) Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation. J Bone Joint Surg Br 84(1):15–18. https://doi.org/10.1302/0301-620x.84b1.11347

    Article  CAS  PubMed  Google Scholar 

  11. Kumagai K, Yamada S, Nejima S, Muramatsu S, Akamatsu Y, Inaba Y (2020) Lateral hinge fracture delays healing of the osteotomy gap in opening wedge high tibial osteotomy with a beta-tricalcium phosphate block. Knee 27(1):192–197. https://doi.org/10.1016/j.knee.2019.10.027

    Article  PubMed  Google Scholar 

  12. Bei T, Yang L, Huang Q, Wu J, Liu J (2022) Effectiveness of bone substitute materials in opening wedge high tibial osteotomy: a systematic review and meta-analysis. Ann Med 54(1):565–577

    Article  PubMed  PubMed Central  Google Scholar 

  13. Goshima K, Sawaguchi T, Shigemoto K, Iwai S, Fujita K, Kataoka T, Taninaka A (2020) Factors associated with patient satisfaction after opening-wedge high tibial osteotomy. Orthop J Sports Med 8(11):2325967120967964. https://doi.org/10.1177/2325967120967964

    Article  PubMed  PubMed Central  Google Scholar 

  14. Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P (2014) Does obesity and nicotine abuse influence the outcome and complication rate after open-wedge high tibial osteotomy? a retrospective evaluation of five hundred and thirty three patients. Int Orthop 38(1):55–60. https://doi.org/10.1007/s00264-013-2082-3

    Article  PubMed  Google Scholar 

  15. Neirynck J, van Beek N, Claes T, Claes S, Bartholomeeusen S (2021) Simultaneous bilateral opening-wedge high tibial osteotomy with structural allograft impaction results in excellent early recovery and pain reduction similar unilateral osteotomy. Knee 30:283–290

    Article  CAS  PubMed  Google Scholar 

  16. Van Genechten W, Van den Bempt M, Van Tilborg W, Bartholomeeusen S, Van Den Bogaert G, Claes T, Claes S (2020) Structural allograft impaction enables fast rehabilitation in opening-wedge high tibial osteotomy: a consecutive case series with one year follow-up. Knee Surg Sports Traumatol Arthrosc 28(12):3747–3757. https://doi.org/10.1007/s00167-019-05765-z

    Article  PubMed  Google Scholar 

  17. Kuremsky MA, Schaller TM, Hall CC, Roehr BA, Masonis JL (2010) Comparison of autograft vs allograft in opening-wedge high tibial osteotomy. J Arthroplast 25(6):951–957. https://doi.org/10.1016/j.arth.2009.07.026

    Article  Google Scholar 

  18. Darees M, Putman S, Brosset T, Roumazeille T, Pasquier G, Migaud H (2018) Opening-wedge high tibial osteotomy performed with locking plate fixation (Tomofix) and early weight-bearing but without filling the defect a concise follow-up note of 48 cases at 10 years’ follow-up. Orthop Traumatol Surg Res OTSR 104(4):477–480. https://doi.org/10.1016/j.otsr.2017.12.021

    Article  CAS  PubMed  Google Scholar 

  19. Zaki SH, Rae PJ (2009) High tibial valgus osteotomy using the Tomofix plate–medium-term results in young patients. Acta Orthop Belg 75(3):360–367

    PubMed  Google Scholar 

  20. Sabzevari S, Ebrahimpour A, Roudi MK, Kachooei AR (2016) High tibial osteotomy: a systematic review and current concept. Arch Bone Joint Surg 4(3):204–212

    PubMed  PubMed Central  Google Scholar 

  21. Golovakha ML, Orljanski W, Benedetto KP, Panchenko S, Büchler P, Henle P, Aghayev E (2014) Comparison of theoretical fixation stability of three devices employed in medial opening wedge high tibial osteotomy: a finite element analysis. BMC Musculoskelet Disord 15:230. https://doi.org/10.1186/1471-2474-15-230

    Article  Google Scholar 

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Correspondence to Hosein Karimi Haris.

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The authors declare no conflict of interest to disclose.

Ethical statement

This study was approved by the review board of our institute under the code IR.IUMS.REC.1400.899. Patients provided written consent before participation in the study.

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Yazdi, H.R., Karimi Haris, H., Rohani, S. et al. The results of allogenic cancellous bone graft in medial opening wedge high tibial osteotomy. Eur J Orthop Surg Traumatol 33, 623–627 (2023). https://doi.org/10.1007/s00590-022-03335-7

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  • DOI: https://doi.org/10.1007/s00590-022-03335-7

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