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Custom-made, antibiotic-loaded, acrylic cement spacers using a dental silicone template for treatment of infected hip prostheses

  • Original Article • HIP - INFECTION
  • Published:
European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Purpose

Antibiotic-loaded acrylic cement (ALAC) spacers are useful for treatment of infected prostheses in the course of a two-stage revision. Spacers are handmade or are made using a commercial template, with reportedly good treatment outcomes. This study aimed to confirm the usefulness of custom-made ALAC spacers shaped like bipolar hip prostheses using a dental silicone template for treatment of infected hip prostheses, and described their manufacture.

Methods

This study evaluated 10 patients who underwent two-stage revision for treatment of infected hip prostheses. Custom-made ALAC spacers were used in all patients. Templates were made with dental silicone. We investigated the following in treatment of the infected hip prostheses: bacterial pathogens; antibiotic-cement mixtures; waiting time to revision; dislocation, breakage, and migration of custom-made ALAC spacers; current hip status; progress during follow-up; presence or absence of recurrence; and walking ability.

Results

Dislocation, breakage, and migration were not observed in custom-made ALAC spacers. All patients recovered after two-stage revision without additional surgery and showed no recurrence during the follow-up period.

Conclusion

Custom-made ALAC spacers shaped like bipolar hip prostheses using a template made of dental silicone may be useful for treatment of infected hip prostheses.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Tokyo Women’s Medical University, 8-1 Kawada-Cho, Shinjuku Ward, Tokyo, 162-8666, Japan

    Tadahiko Ohtsuru, Yuji Morita, Yutaro Munakata, Masafumi Itoh & Ken Okazaki

  2. Department of Orthopaedic Surgery, Teikyo University, Chiba, Japan

    Yasuaki Murata

  3. Kita Shinagawa 3rd Hospital, Shinagawa Ward, Tokyo, Japan

    Yoshiharu Kato

Authors
  1. Tadahiko Ohtsuru
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  2. Yuji Morita
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  3. Yasuaki Murata
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  4. Yutaro Munakata
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  5. Masafumi Itoh
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  6. Yoshiharu Kato
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  7. Ken Okazaki
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Corresponding author

Correspondence to Tadahiko Ohtsuru.

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Conflict of interest

Tadahiko Ohtsuru, Yuji Morita, Yasuaki Murata, Yutaro Munakata, Masafumi Itoh, Yoshiharu Kato, and Ken Okazaki declare that they have no conflict of interest.

Ethical approval

This study was approved on May 12, 2017 by the Ethics Committee of Tokyo Women’s University (Reference Number 4367) and was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Written informed consent was obtained from all patients, who were fully informed that their data would be submitted for publication.

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Ohtsuru, T., Morita, Y., Murata, Y. et al. Custom-made, antibiotic-loaded, acrylic cement spacers using a dental silicone template for treatment of infected hip prostheses. Eur J Orthop Surg Traumatol 28, 615–620 (2018). https://doi.org/10.1007/s00590-017-2117-3

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  • DOI: https://doi.org/10.1007/s00590-017-2117-3

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