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Efficacy of the magnetic stimulation of sacral nerve roots combined with Tui-na on neurogenic bladder after spinal cord injury: preliminary short-term results

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Abstract

Objective

Neurogenic bladder (NGB) is a serious complication after spinal cord injury (SCI), a destructive neurological disease. This study focused on exploring the efficacy of the magnetic stimulation of sacral nerve roots combined with Tui-na in treating NGB after SCI.

Methods

One hundred patients with NGB after SCI were studied, and intermittent clean catheterization was performed with a water intake program, and patients were grouped into four groups by the random number table method: general treatment group, Tui-na group, magnetic stimulation group, and combined treatment group. A series of relevant factors (voiding diary, urodynamics, and quality of life scores) and clinical efficacy of patients in the four groups before and after treatment were observed.

Results

The magnetic stimulation of sacral nerve roots alone, Tui-na alone, and the combination of both were all effective in improving bladder function and quality of life in patients with NGB after SCI, including improvements in voiding frequency, single urine output, maximum urine output, residual urine output, bladder volume and quality of life scores in patients with NGB after SCI. The efficacy of the magnetic stimulation of sacral nerve roots combined with Tui-na was better than that of the magnetic stimulation of sacral nerve roots alone and the Tui-na alone.

Conclusion

This research demonstrates that the magnetic stimulation of sacral nerve roots combined with Tui-na treatment could effectively improve the urinary system and the quality of life of patients with NGB after SCI, which is worthy of clinical promotion and application.

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References

  1. Quadri SA, Farooqui M, Ikram A, Zafar A, Khan MA, Suriya SS, Claus CF, Fiani B, Rahman M, Ramachandran A, Armstrong IIT, Taqi MA, Mortazavi MM (2020) Recent update on basic mechanisms of spinal cord injury. Neurosurg Rev 43(2):425–441. https://doi.org/10.1007/s10143-018-1008-3

    Article  PubMed  Google Scholar 

  2. Shu J, Cheng F, Gong Z, Ying L, Wang C, Yu C, Zhou X, Xiao M, Wang J, Xia K, Huang X, Tao Y, Shi K, Liu Y, Liang C, Chen Q, Feng X, Li F (2020) Transplantation strategies for spinal cord injury based on microenvironment modulation. Curr Stem Cell Res Ther 15(6):522–530. https://doi.org/10.2174/1574888X15666200421112622

    Article  CAS  PubMed  Google Scholar 

  3. Hamid R, Averbeck MA, Chiang H, Garcia A, Al Mousa RT, Oh SJ, Patel A, Plata M, Del Popolo G (2018) Epidemiology and pathophysiology of neurogenic bladder after spinal cord injury. World J Urol 36(10):1517–1527. https://doi.org/10.1007/s00345-018-2301-z

    Article  PubMed  Google Scholar 

  4. Redshaw JD, Lenherr SM, Elliott SP, Stoffel JT, Rosenbluth JP, Presson AP, Myers JB (2018) Protocol for a randomized clinical trial investigating early sacral nerve stimulation as an adjunct to standard neurogenic bladder management following acute spinal cord injury. BMC Urol 18(1):1–8. https://doi.org/10.1186/s12894-018-0383-y

    Article  Google Scholar 

  5. Liao L (2015) Evaluation and management of neurogenic bladder: what is new in China? Int J Mol Sci 16(8):18580–18600. https://doi.org/10.3390/ijms160818580

    Article  PubMed  PubMed Central  Google Scholar 

  6. Romo PGB, Smith CP, Cox A, Averbeck MA, Dowling C, Beckford C, Manohar P, Duran S, Cameron AP (2018) Non-surgical urologic management of neurogenic bladder after spinal cord injury. World J Urol 36(10):1555–1568. https://doi.org/10.1007/s00345-018-2419-z

    Article  PubMed  Google Scholar 

  7. Braga A, Castronovo F, Caccia G, Papadia A, Regusci L, Torella M, Salvatore S, Scancarello C, Ghezzi F, Serati M (2022) Efficacy of 3 tesla functional magnetic stimulation for the treatment of female urinary incontinence. J Clin Med. https://doi.org/10.3390/jcm11102805

    Article  PubMed  PubMed Central  Google Scholar 

  8. Peters KM (2010) Alternative approaches to sacral nerve stimulation. Int Urogynecol J 21(12):1559–1563. https://doi.org/10.1007/s00192-010-1282-2

    Article  PubMed  Google Scholar 

  9. Liu LQ, Ferguson-Pell M (2015) Pressure changes under the ischial tuberosities during gluteal neuromuscular stimulation in spinal cord injury: a comparison of sacral nerve root stimulation with surface functional electrical stimulation. Arch Phys Med Rehabil 96(4):620–626. https://doi.org/10.1016/j.apmr.2014.10.008

    Article  PubMed  Google Scholar 

  10. Harris ML, Singh S, Rothwell J, Thompson DG, Hamdy S (2008) Rapid rate magnetic stimulation of human sacral nerve roots alters excitability within the cortico-anal pathway. Neurogastroenterol Motil 20(10):1132–1139. https://doi.org/10.1111/j.1365-2982.2008.01153.x

    Article  CAS  PubMed  Google Scholar 

  11. Bycroft JA, Craggs MD, Sheriff M, Knight S, Shah PJ (2004) Does magnetic stimulation of sacral nerve roots cause contraction or suppression of the bladder? Neurourol Urodyn 23(3):241–245. https://doi.org/10.1002/nau.20009

    Article  CAS  PubMed  Google Scholar 

  12. Fujishiro T, Takahashi S, Enomoto H, Ugawa Y, Ueno S, Kitamura T (2002) Magnetic stimulation of the sacral roots for the treatment of urinary frequency and urge incontinence: an investigational study and placebo controlled trial. J Urol 168(3):1036–1039. https://doi.org/10.1097/01.ju.0000025868.08859.9e

    Article  PubMed  Google Scholar 

  13. Zou G, Wang G, Li J, Wu G, Huang J, Huang S (2017) Danger of injudicious use of Tui-na therapy in ankylosing spondylitis. Eur Spine J 26(Suppl 1):178–180. https://doi.org/10.1007/s00586-017-5002-1

    Article  PubMed  Google Scholar 

  14. Wei X, Wang S, Li L, Zhu L (2017) Clinical evidence of chinese massage therapy (Tui Na) for cervical radiculopathy: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2017:9519285. https://doi.org/10.1155/2017/9519285

    Article  PubMed  PubMed Central  Google Scholar 

  15. Zhu Q, Li J, Fang M, Gong L, Sun W, Zhou N (2016) Effect of Chinese massage (Tui Na) on isokinetic muscle strength in patients with knee osteoarthritis. J Tradit Chin Med 36(3):314–320. https://doi.org/10.1016/s0254-6272(16)30043-7

    Article  PubMed  Google Scholar 

  16. Vasquez N, Gall A, Ellaway PH, Craggs MD (2013) Light touch and pin prick disparity in the international standard for neurological classification of spinal cord injury (ISNCSCI). Spinal Cord 51(5):375–378. https://doi.org/10.1038/sc.2012.175

    Article  CAS  PubMed  Google Scholar 

  17. Zhao Y, Wang D, Zou L, Mao L, Yu Y, Zhang T, Bai B, Chen Z (2022) Comparison of the efficacy and safety of sacral root magnetic stimulation with transcutaneous posterior tibial nerve stimulation in the treatment of neurogenic detrusor overactivity: an exploratory randomized controlled trial. Transl Androl Urol 11(6):821–831. https://doi.org/10.21037/tau-22-249

    Article  PubMed  PubMed Central  Google Scholar 

  18. Ginsberg D (2013) Optimizing therapy and management of neurogenic bladder. Am J Manag Care 19(10 Suppl):s197-204

    PubMed  Google Scholar 

  19. MaLossi J, Chai TC (2002) Sacral neuromodulation for the treatment of bladder dysfunction. Curr Urol Rep 3(1):61–66. https://doi.org/10.1007/s11934-002-0012-9

    Article  PubMed  Google Scholar 

  20. Li J, Cai S, Zeng C, Chen L, Zhao C, Huang Y, Cai W (2022) Urinary exosomal vitronectin predicts vesicoureteral reflux in patients with neurogenic bladders and spinal cord injuries. Exp Ther Med 23(1):65. https://doi.org/10.3892/etm.2021.10988

    Article  CAS  PubMed  Google Scholar 

  21. Lucas E (2019) Medical management of neurogenic bladder for children and adults: a review. Top Spinal Cord Inj Rehabil 25(3):195–204. https://doi.org/10.1310/sci2503-195

    Article  PubMed  PubMed Central  Google Scholar 

  22. Taweel WA, Seyam R (2015) Neurogenic bladder in spinal cord injury patients. Res Rep Urol 7:85–99. https://doi.org/10.2147/RRU.S29644

    Article  PubMed  PubMed Central  Google Scholar 

  23. Balsara ZR, Ross SS, Dolber PC, Wiener JS, Tang Y, Seed PC (2013) Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder. Infect Immun 81(8):3018–3026. https://doi.org/10.1128/IAI.00255-13

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Cooley LF, Kielb S (2019) A review of botulinum toxin a for the treatment of neurogenic bladder. PM R 11(2):192–200. https://doi.org/10.1016/j.pmrj.2018.07.016

    Article  PubMed  Google Scholar 

  25. Liem SS, Demus T, Jivanji D, Palmerola R (2022) Bullseye technique to optimize S3 foramen access: applying a trusted endourology technique to pelvic medicine. Urology. https://doi.org/10.1016/j.urology.2022.10.011

    Article  PubMed  Google Scholar 

  26. Deng DY, Gulati M, Rutman M, Raz S, Rodriguez LV (2006) Failure of sacral nerve stimulation due to migration of tined lead. J Urol 175(6):2182–2185. https://doi.org/10.1016/S0022-5347(06)00318-1

    Article  PubMed  Google Scholar 

  27. Brouillard CBJ, Crook JJ, Lovick TA (2019) Suppression of urinary voiding “on Demand” by high-frequency stimulation of the S1 sacral nerve root in anesthetized Rats. Neuromodulation 22(6):703–708. https://doi.org/10.1111/ner.12928

    Article  PubMed  Google Scholar 

  28. Liu LQ, Ferguson-Pell M (2019) Blood perfusion changes during sacral nerve root stimulation versus surface gluteus electrical stimulation on in seated spinal cord injury. Assist Technol 31(1):1–8. https://doi.org/10.1080/10400435.2017.1340360

    Article  CAS  PubMed  Google Scholar 

  29. Irwin GW, Dasari BV, Irwin R, Johnston D, Khosraviani K (2017) Outcomes of sacral nerve stimulation for faecal incontinence in northern Ireland. Ulster Med J 86(1):20–24

    CAS  PubMed  PubMed Central  Google Scholar 

  30. Liu LQ, Nicholson GP, Knight SL, Chelvarajah R, Gall A, Middleton FR, Ferguson-Pell MW, Craggs MD (2006) Pressure changes under the ischial tuberosities of seated individuals during sacral nerve root stimulation. J Rehabil Res Dev 43(2):209–218. https://doi.org/10.1682/jrrd.2005.04.0078

    Article  PubMed  Google Scholar 

  31. Shubov A, Taw L (2015) Treatment of posttraumatic abdominal autonomic neuropathy manifesting as functional dyspepsia and chronic constipation: an integrative east-west approach. Glob Adv Health Med 4(4):56–60. https://doi.org/10.7453/gahmj.2014.081

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Rehabilitation, The First People’s Hospital of Fuyang, 429 Beihuan Road, Fuyang District, Hangzhou, 311400, Zhejiang, China

    Lin Chen & Yunbo Li

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Chen, L., Li, Y. Efficacy of the magnetic stimulation of sacral nerve roots combined with Tui-na on neurogenic bladder after spinal cord injury: preliminary short-term results. Eur Spine J 32, 2441–2447 (2023). https://doi.org/10.1007/s00586-023-07760-y

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