Skip to main content

Advertisement

Log in

The use of vacuum-assisted closure in spinal wound infections with or without exposed dura

  • Original Article
  • Published:
European Spine Journal Aims and scope Submit manuscript

Abstract

Introduction

The treatment of postoperative deep spinal wound infection involves debridement and intravenous antibiotics. Authors have previously reported success in a small series of patients treated with vacuum-assisted closure (VAC) therapy, but its use over exposed dura is controversial and the outcome has not been reported in large series.

Purpose

To review the outcomes following the treatment of postoperative spinal infections with VAC therapy, particularly those with exposed dura.

Methods

This is a review of prospectively collected data in 42 patients, all of whom had deep postoperative spinal infections. 30 of these patients had exposed dura. All patients had an initial debridement followed by application of VAC Whitefoam (with exposed dura) or grey Granufoam (where no dura was exposed). Pressure was set at 50 mmHg with exposed dura or 125 mmHg where no dura was exposed. All patients underwent a minimum 6 week course of antibiotics. We report on the number of visits to theatre required for dressing changes and debridement and the eventual outcomes.

Results

Five patients required a flap reconstruction. Two patients died before definitive final closure due to other complications (pneumonia and stroke). In all the other patients, their wounds healed fully. A mean of 2.3 infection surgeries were required to eradicate infection and achieve wound closure.

Conclusions

This is one of the largest studies which confirms the safety and efficacy of VAC dressings in patients with spinal wound infections, even when the dura is exposed.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Weinstein MA, McCabe JP, Cammisa FP (2000) Postoperative spinal wound infection: a review of 2391 consecutive index procedures. J Spinal Disord 13:422–426

    Article  CAS  Google Scholar 

  2. Malamo-Lada H, Zarkotou O, Nikolaides N et al (1999) Wound infections following posterior spinal instrumentation for paralytic scoliosis. Clin Microbiol Infect 5:135–139

    Article  Google Scholar 

  3. Glassman SD, Dimar JR, Puno RM, Johnson JR (1996) Salvage of instrumental lumbar fusions complicated by surgical wound infection. Spine 21:2163–2169

    Article  CAS  Google Scholar 

  4. Calderone RR, Garland DE, Capen DA, Oster H (1996) Cost of medical care for postoperative spinal infections. Orthop Clin N Am 27:171–182

    CAS  Google Scholar 

  5. Saxena V, Hwang C-W, Huang S et al (2004) Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg 114:1086–1096

    Article  Google Scholar 

  6. Canavese F, Gupta S, Krajbich JI, Emara KM (2008) Vacuum-assisted closure for deep infection after spinal instrumentation for scoliosis. J Bone Joint Surg Br 90:377–381

    Article  CAS  Google Scholar 

  7. Jones GA, Butler J, Lieberman I, Schlenk R (2007) Negative-pressure wound therapy in the treatment of complex postoperative spinal wound infections: complications and lessons learned using vacuum-assisted closure. J Neurosurg Spine 6:407–411

    Article  Google Scholar 

  8. Mehbod A, Ogilvie JW, Pinto MR et al (2005) Postoperative deep wound infections in adults after spinal fusion: management with vacuum-assisted wound closure. J Spinal Disord Tech 18:14–17

    Article  CAS  Google Scholar 

  9. Ploumis A, Mehbod A, Dressel TD et al (2008) Therapy of spinal wound infections using vacuum-assisted wound closure: risk factors leading to resistance to treatment. J Spinal Disord Tech 21:320–323

    Article  Google Scholar 

  10. Powers AK, Neal MT, Argenta LC et al (2013) Vacuum-assisted closure for complex cranial wounds involving the loss of dura mater. J Neurosurg 118:302–308

    Article  Google Scholar 

  11. Subotic U, Kluwe W, Oesch V (2011) Community-associated methicillin-resistant staphylococcus aureus-infected chronic scalp wound with exposed dura in a 10-year-old boy: vacuum-assisted closure is a feasible option: case report. Neurosurgery 68:E1481–E1484

    Article  Google Scholar 

  12. Marathe US, Sniezek JC (2004) Use of the vacuum-assisted closure device in enhancing closure of a massive skull defect. Laryngoscope 114:961–964

    Article  Google Scholar 

  13. Walma MS, Burbach JPM, Verheijen PM et al (2016) Vacuum-assisted closure therapy for infected perineal wounds after abdominoperineal resection. A retrospective cohort study. Int J Surg 26:18–24

    Article  CAS  Google Scholar 

  14. Yoshimoto A, Inoue T, Fujisaki M et al (2016) Efficacy of vacuum-assisted closure therapy on rehabilitation during the treatment for surgical site infection after cardiovascular surgery. Gen Thorac Cardiovasc Surg 64:464–469

    Article  Google Scholar 

  15. Lambert KV, Hayes P, McCarthy M (2005) Vacuum assisted closure: a review of development and current applications. Eur J Vasc Endovasc Surg 29:219–226

    Article  CAS  Google Scholar 

  16. Gabriel A, Shores J, Bernstein B et al (2009) A clinical review of infected wound treatment with (V.A.C.) therapy: experience and case series. Int Wound J 6:221–225

    Article  Google Scholar 

  17. DeFranzo AJ, Argenta LC, Marks MW et al (2001) The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone. Plast Reconstr Surg 108:1184–1191

    Article  CAS  Google Scholar 

  18. Picada R, Winter RB, Lonstein JE et al (2000) Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation: incidence and management. J Spinal Disord 13:42–45

    Article  CAS  Google Scholar 

  19. Mithani SK, Tufaro AP (2006) Management of wound complications in spinal surgery. Neurosurg Q 16:9–14

    Article  Google Scholar 

  20. Tsubouchi N, Fujibayashi S, Otsuki B et al (2017) Risk factors for implant removal after spinal surgical site infection. Eur Spine J. https://doi.org/10.1007/s00586-017-5294-1

    Article  PubMed  Google Scholar 

  21. Muschik M, Lück W, Schlenzka D (2004) Implant removal for late-developing infection after instrumented posterior spinal fusion for scoliosis: reinstrumentation reduces loss of correction. A retrospective analysis of 45 cases. Eur Spine J 13:645–651

    Article  Google Scholar 

  22. Collins I, Wilson-MacDonald J, Chami G et al (2008) The diagnosis and management of infection following instrumented spinal fusion. Eur Spine J 17:445–450

    Article  Google Scholar 

  23. Vitaz TW, Oishi M, Welch WC et al (2004) Rotational and transpositional flaps for the treatment of spinal wound dehiscence and infections in patient populations with degenerative and oncological disease. J Neurosurg 100:46–51

    PubMed  Google Scholar 

  24. Abbas Khan MA, Chipp E, Hardwicke J et al (2010) The use of dermal regeneration template (Integra®) for reconstruction of a large full-thickness scalp and calvarial defect with exposed dura. J Plast Reconstr Aesthet Surg 63:2168–2171

    Article  Google Scholar 

  25. Donovan DJ, Person DA (2006) Giant eccrine adenocarcinoma of the scalp with intracranial invasion: resection and reconstruction using a vacuum-assisted closure device: technical case report. Neurosurgery 58(4 Suppl 2):E371

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Robert Lee.

Ethics declarations

Conflict of interest

The authors declare that they have no potential conflict of interest.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (PPTX 388 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lee, R., Beder, D., Street, J. et al. The use of vacuum-assisted closure in spinal wound infections with or without exposed dura. Eur Spine J 27, 2536–2542 (2018). https://doi.org/10.1007/s00586-018-5612-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00586-018-5612-2

Keywords

Navigation