Abstract
Purpose
Given that the disc moves simultaneously with facet joints, there would be a relationship between Modic changes and facet joint degeneration in the cervical spine. However, there is no literature investigating the relationship. The purpose is to evaluate the relationship between Modic changes and facet joint degeneration in the cervical spine.
Methods
Ninety-eight patients underwent both computed tomography (CT) and magnetic resonance images (MRI) of the cervical spine. They consisted of fifty-one males and forty-eight females and their mean age was 60.1 years (ranged from 40 years to 81 years). We compared the degree of facet joint degeneration based on CTs with Modic changes based on MRIs from C2–C3 to C6–C7. The degree of facet joint degeneration was classified into four categories and Modic changes were classified into four types. Disc degeneration was determined with Miyazaki’s grading system.
Results
Facet joint degeneration was most common at C2–C3 and C4–C5 and rarest at C6–C7. Modic changes were most common at C2–C3 and rarest at C6–C7. However, there was no relationship between facet joint degeneration and any Modic changes at the same level. However, the presence of facet joint degeneration and the presence of Modic change are common in high grades of disc degeneration at the same level of the cervical spine.
Conclusion
Modic changes and facet joint degeneration are most common at C2–C3 in the cervical spine. However, there were no relationships between the presence of Modic changes and facet joint degeneration at the same level of the cervical spine.
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References
Matsumoto M, Okada E, Ichihara D, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Takahata T (2012) Modic changes in the cervical spine: prospective 10-year follow-up study in asymptomatic subjects. J Bone Joint Surg Br 94:678–683. doi:10.1302/0301-620X.94B5.28519
Peterson CK, Humphreys BK, Pringle TC (2007) Prevalence of modic degenerative marrow changes in the cervical spine. J Manipulative Physiol Ther 30:5–10. doi:10.1016/j.jmpt.2006.11.013
Hayashi T, Daubs MD, Suzuki A, Phan K, Shiba K, Wang JC (2014) Effect of Modic changes on spinal canal stenosis and segmental motion in cervical spine. Eur Spine J. doi:10.1007/s00586-014-3406-8
Mann E, Peterson CK, Hodler J (2011) Degenerative marrow (modic) changes on cervical spine magnetic resonance imaging scans: prevalence, inter- and intra-examiner reliability and link to disc herniation. Spine (Phila Pa 1976) 36:1081–1085. doi:10.1097/BRS.0b013e3181ef6a1e
Master DL, Toy JO, Eubanks JD, Ahn NU (2012) Cervical Endplate and Facet Arthrosis: An Anatomic Study of Cadaveric Specimens. J Spinal Disord Tech 25:379–382. doi:10.1097/BSD.0b013e318224a60f
Park MS, Moon SH, Lee HM, Kim TH, Oh JB, Riew KD (2014) Facet joint degeneration of the cervical spine: a computed tomographic analysis of 320 patients. Spine 39:E713–E718
Miyazaki M, Hong SW, Yoon SH, Morishita Y, Wang JC (2008) Reliability of a magnetic resonance imaging-based grading system for cervical intervertebral disc degeneration. J Spinal Disord Tech 21:288–292. doi:10.1097/BSD.0b013e31813c0e59
Braithwaite I, White J, Saifuddin A, Renton P, Taylor BA (1998) Vertebral end-plate (Modic) changes on lumbar spine MRI: correlation with pain reproduction at lumbar discography. Eur Spine J 7:363–368
Kjaer P, Korsholm L, Bendix T, Sorensen JS, Leboeuf-Yde C (2006) Modic changes and their associations with clinical findings. Eur Spine J 15:1312–1319. doi:10.1007/s00586-006-0185-x
Zhang YH, Zhao CQ, Jiang LS, Chen XD, Dai LY (2008) Modic changes: a systematic review of the literature. Eur Spine J 17:1289–1299. doi:10.1007/s00586-008-0758-y
Jensen TS, Karppinen J, Sorensen JS, Niinimaki J, Leboeuf-Yde C (2008) Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain. Eur Spine J 17:1407–1422. doi:10.1007/s00586-008-0770-2
Wang Y, Videman T, Battie MC (2012) Modic changes: prevalence, distribution patterns, and association with age in white men. Spine J 12:411–416. doi:10.1016/j.spinee.2012.03.026
Mann E, Peterson CK, Hodler J, Pfirrmann CW (2014) The evolution of degenerative marrow (Modic) changes in the cervical spine in neck pain patients. Eur Spine J 23:584–589. doi:10.1007/s00586-013-2882-6
Kuisma M, Karppinen J, Niinimaki J, Ojala R, Haapea M, Heliovaara M, Korpelainen R, Taimela S, Natri A, Tervonen O (2007) Modic changes in endplates of lumbar vertebral bodies: prevalence and association with low back and sciatic pain among middle-aged male workers. Spine (Phila Pa 1976) 32:1116–1122. doi:10.1097/01.brs.0000261561.12944.ff
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Author K. Daniel Riew is a member of CSRS, KASS, received royalties from Osprey, Biomet, Medtronic Sofamor Danek and owns stock in Osprey, Expanding Orthopedics, Spineology, Spinal Kinetics, Amedica, Nexgen Spine, Vertiflex, Benvenue, Paradigm Spine, PSD. The other authors declare that they have no conflict of interest.
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Park, M.S., Moon, SH., Kim, TH. et al. Relationship between modic changes and facet joint degeneration in the cervical spine. Eur Spine J 24, 2999–3004 (2015). https://doi.org/10.1007/s00586-015-4257-7
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DOI: https://doi.org/10.1007/s00586-015-4257-7