Abstract
Purpose
Spinal metastases are common in patients with cancer. Following lung and liver, spine is the most common site for cancers to metastasize. Many of them are hypervascularized. These cases are a particular challenge for the surgeon and represent a significant danger of massive blood loss during surgery. Hypervascularized metastases of the cervical spine also include the risk of postoperative bleeding with severe neurological impairment.
Case summary
We report a case of a 67-year-old women with breast cancer (BC) metastasis within the vertebral bodies of C3 and C4 with nearly complete bony destruction of the ventral column and intraspinal tumor masses compressing the spinal cord at level C3 and C4. The hypervascularized tumor was supplied by multiple minor vessels from both vertebral arteries, too small to be coiled individually. Due to an allergy to aspirin, intravascular stenting of the vertebral arteries was not an option. We decided to perform a preoperative direct injection of onyx-18 for embolization of the tumor.
Conclusion
Presurgical direct injection of Onyx-18 for treating hypervascular spinal metastases of breast cancer seems to be an effective and safe technique and reduces intraoperative bleeding to a minimum.
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Acknowledgments
We thank Katharina Pütz, MD, Institute of Pathology of the University of Cologne, for providing the histological images of the spinal tumor and the description of it.
Conflict of interest
The authors declare that they have no competing interests. We have no personal or financial conflicts of interest related to the preparation and publication of this manuscript.
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Written informed consent for the publication of clinical data was obtained from the patient.
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Oppermann, J., Bredow, J., Siewe, J. et al. Hypervascular cervical spine metastases: embolization by direct injection of Onyx-18. Eur Spine J 24 (Suppl 4), 580–584 (2015). https://doi.org/10.1007/s00586-014-3754-4
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DOI: https://doi.org/10.1007/s00586-014-3754-4