Abstract
Osteochondroma is a proliferative condition that affects cartilage and bone in rare cases. Osteochondroma of the ribs is uncommon in dogs, and its manifestation has the potential to induce compression and harm to the vasculature and internal organs of the thoracic cavity. The discoverable evidence of this condition was encountered during the dissection of the chest of a 5-year-old male dog of mixed breed, who had no previous record of illness. The salient features noted during the dissection process were the identification of four dome-shaped masses which evinced a solid consistency and were found to be located in the right hemithorax, thus leaving an impression on the caudal lobes of the right lung. The masses were distinguished by their smooth surfaces and hard texture. Upon histological analysis, the lesion was characterized by spongy bone enveloped by periosteum and hyaline cartilage. The results obtained from the study’s macroscopic and microscopic levels indicated multiple cartilaginous exostosis.
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The data that support the findings of this study are available from the corresponding author upon reasonable request.
References
Alnassar AS (2021) Rib osteochondroma causing cardiac compression in a pediatric patient. Int J Surg Case Rep 81:105762. https://doi.org/10.1016/j.ijscr.2021.105762
Alyas F, James SL, Davies AM, Saifuddin A (2007) The role of MR imaging in the diagnostic characterisation of appendicular bone tumours and tumour-like conditions. Eur Radiol 17:2675–2686. https://doi.org/10.1007/s00330-007-0597-y
BeBeck JA, Simpson DJ, Tisdall PLC (1999) Surgical management of osteochondromatosis affecting the vertebrae and trachea in an Alaskan Malamute. Aust Vet J 77(1):21–23. https://doi.org/10.1111/j.1751-0813.1999.tb12418.x
Chakravorty A, Fong L, Grant P, Wolfenden H, Akhunji Z (2021) Multiple rib osteochondromas: a rare cause of spontaneous haemothorax. ANZ J Surg 91(10):E666–E667. https://doi.org/10.1111/ans.16705
Correa F, Parra D, González C, Lara F (2017) Radial osteochondroma in a Chilean pure breed rodeo horse: first case reported in this breed. Sustain, Agri, Food Environ Res 4(4):18–26. https://doi.org/10.7770/safer-V4N4-art1115
Czerwik A, Olszewska A, Starzomska B, Korta R, Henrich M, Wrzosek M, Schmidt MJ (2019) Multiple cartilaginous exostoses in a Swiss Mountain dog causing thoracolumbar compressive myelopathy. Acta Vet Scand 61:1–6
de Brot S, Grau-Roma L, Vidal E, Segalés J (2013) Occurrence of osteochondromatosis (multiple cartilaginous exostoses) in a domestic pig (Sus scrofa domesticus). J Vet Diagn Investig 25(5):599–602. https://doi.org/10.1177/1040638713495545
De Salvo S, Pavone V, Coco S, Dell’Agli E, Blatti C, Testa G (2022) Benign bone tumors: an overview of what we know today. J Clin Med 11(3):699. https://doi.org/10.3390/jcm11030699
Doige CE (1987) Multiple cartilaginous exostoses in dogs. Vet Pathol 24(3):276–278. https://doi.org/10.1177/030098588702400314
Engel S, Randall EK, Cuddon PA, Webb BT, Aboellail TA (2014) Imaging diagnosis: multiple cartilaginous exostoses and calcinosis circumscripta occurring simultaneously in the cervical spine of a dog. Vet Radiol Ultrasound 55(3):305–309. https://doi.org/10.1111/vru.12066
Friedenberg SG, Vansteenkiste D, Yost O, Treeful AE, Meurs KM, Tokarz DA, Olby NJ (2018) A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of American Staffordshire Terriers. J Vet Intern Med 32(3):986–992. https://doi.org/10.1111/jvim.15073
Green EM, Adams WM, Steinberg H (1999) Malignant transformation of solitary spinal osteochondroma in two mature dogs. Vet Radiol Ultrasound 40(6):634–637. https://doi.org/10.1111/j.1740-8261.1999.tb00891.x
Jilowa S, Paliwal P, Kapur A, Verma GC (2021) Exostosis of rib: case report of an extremely rare giant osteochondroma at an unusual site, radiopathological correlation with brief review of literature. Indian J Radiol Imaging 31(3):740–744. https://doi.org/10.1055/s-0041-1736406
Jubb KVF, Kennedy PC, Palmer N (1985) Diseases of bone in pathology of domestic animals. Academic Press, San Diego, pp 2–138
Meuten DJ (Ed.) (2020) Tumors in domestic animals. John Wiley & Sons
Milgram JW (1983) The origins of osteochondromas and enchondromas a histopathologic study. Clin Orthop Relat Res 174:264–284
Misdorp W, Van der Heul RO (1976) Tumours of bones and joints. Bull World Health Organ 53(2–3):265
Morgan JP, Carlson WD, Adams OR (1962) Hereditary multiple exostosis in the horse. J Am Vet Med Assoc 140:1320–1322
Motamedi K, Seeger LL (2011) Benign bone tumors. Radiol Clin 49(6):1115–1134. https://doi.org/10.1016/j.rcl.2011.07.002
Niemand HG, Suter PF, Arnold P, Pomorski Z, Nicpoń J, Zduńczyk S, Glazer T (2003) Praktyka kliniczna: psy. Pro-Trade
Pacifici M (2017) Hereditary multiple exostoses: new insights into pathogenesis, clinical complications, and potential treatments. Curr Osteoporos Rep 15:142–152. https://doi.org/10.1007/s11914-017-0355-2
Pool RR, Carrig CB (1972) Multiple cartilaginous exostoses in a cat. Vet Pathol 9(5):350–359. https://doi.org/10.1177/030098587200900505
Riddle WE Jr (1970) Osteochondromatosis in a cat. J Am Vet Med Assoc 156:1428–1430
Saglik Y, Altay M, Unal VS, Basarir K, Yildiz Y (2006) Manifestations and management of osteochondromas: a retrospective analysis of 382 patients. Acta Orthop Belg 72(6):748
Thompson KG, Pool RR (2002) Tumors of bones. Tumors in Domestic Animals 4:245–317. https://doi.org/10.1002/9780470376928
Tvedten E, Richardson J, Husien T, Zghouzi M (2021) Horner syndrome secondary to osteochondroma of the first rib: a case report. Cureus 13(4):4–8. https://doi.org/10.7759/cureus.14531
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Azizi, S., Delshad, S., Sajjadian, S.M. et al. Multiple cartilaginous exostoses of rib in dog: a case report. Comp Clin Pathol 33, 1–5 (2024). https://doi.org/10.1007/s00580-023-03529-3
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DOI: https://doi.org/10.1007/s00580-023-03529-3