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First report of diffuse cutaneous canine transmissible venereal tumor in Iran

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Abstract

Canine transmissible venereal tumor, also known as infectious sarcoma, venereal granuloma, transmissible lymphosarcoma, or sticker tumor, is a type of canine tumor that mainly affects the external genitalia, i.e., the vagina in bitches and the penis and prepuce in males. The tumor is usually nonmalignant, but metastasis to regional lymph nodes, spleen, liver, kidney, lung, brain, and skin has been reported in <6 % of cases. In this clinical case report, one 9-year-old, castrated male terrier dog was referred to Iranmehr Companion Animal Clinic in Mashhad, Iran, with multiple cutaneous cauliflower-shaped masses. Cytologic preparations of lesions revealed a population of round- to oval-shaped cells, with lightly basophilic cytoplasm that contained multiple distinct vacuoles. The clinical and histologic diagnosis was cutaneous transmissible venereal tumor in the progressing growth phase. Thoracic X-ray and abdominal ultrasonography did not show any internal metastasis. Large mass excisions under general anesthesia and further chemotherapy with vincristine sulfate induced clinical remission without recurrence during 9 months of follow-up. To the best of our knowledge, this is the first report of naturally occurring diffuse cutaneous transmissible venereal tumor in a mature male dog in Iran. It has been reported to be unique in that it is exclusively cutaneous without mucosal, subcutaneous, and other organ involvement.

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Acknowledgments

The authors really appreciate to staff members of Iranmehr Companion Animal Clinic in Mashhad, Iran, for their continuous follow-ups. This study was presented in 18th Annual Conference of the Iranian Veterinary Congress, 6–8 April 2014, Tehran, Iran, as a poster.

Conflict of interest

None of the authors of this paper has a financial or personal relationship with other people or organizations that could inappropriately influence or bias the content of the paper.

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Authors and Affiliations

  1. Department of Clinical Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, 1793-91775, Mashhad, Iran

    Mohsen Champour

  2. Private practitioner, Iranmeher Companion Animal Clinic, Mashhad, Iran

    Najmoddin Ojrati

  3. Iranmehr Companion Animal Clinic, Mashhad, Iran

    Arefeh Nikrou & Hedyeh Rahimian

  4. Department of Pathobiology, School of Veterinary Medicine, Azad University of Garmsar, Garmsar, Iran

    Maysam Tehrani-Sharif

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  1. Mohsen Champour
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  2. Najmoddin Ojrati
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  3. Arefeh Nikrou
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  4. Hedyeh Rahimian
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  5. Maysam Tehrani-Sharif
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Correspondence to Mohsen Champour.

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Champour, M., Ojrati, N., Nikrou, A. et al. First report of diffuse cutaneous canine transmissible venereal tumor in Iran. Comp Clin Pathol 24, 741–744 (2015). https://doi.org/10.1007/s00580-014-1973-z

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  • DOI: https://doi.org/10.1007/s00580-014-1973-z

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