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A non enzymatic glutamate sensor based on nickel oxide nanoparticle

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Abstract

This work reports an enzyme-less glutamate sensor based on nickel oxide modified glassy carbon electrode. The nanoparticles of NiO were synthesized by sol–gel method, and showed high electro-catalytic activity towards glutamate oxidation in 0.1 M NaOH solution. The sensor displays a fast response time of < 5 s and a linear dependency of R2 0.997 for glutamate concentration of up to 8 mM at an applied potential of + 0.55 V with a sensitivity of 11 µA mM−1 cm−2 and a detection limit of 272 μM (S/N = 3). The interference studies of NiO/GC electrode showed a significant current response for glutamate in the presence of uric acid and ascorbic acid. Thereby, this simple NiO nanoparticle based sensor can be promising platform for the development of a robust enzymeless glutamate sensor.

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Acknowledgements

Authors acknowledge financial support from the Ministry of Science and Technology, Bangladesh funded project “FACSens” under the special allocation to Science and Technology Activity (2015/2016) programme; and Science Foundation Ireland funded project “SweatSens” under the Grant Agreement No. 14/TIDA/2455. This study was partly supported by the Grant-in-Aid for Scientific Research (Category A, Project No. 17H01224, etc.) from the Japan Society for the Promotion of Science (JSPS), the Centre Of Innovation (COI) program from the Japan Science and Technology Agency (JST), the Strategic Innovation Creation Project (SIP) from the New Energy and Industrial Technology Development Organization (NEDO) of Japan, and the Program on Open Innovation Platform with Enterprises, Research Institute and Academia (OPERA) from the JST.

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Authors and Affiliations

  1. Department of Chemistry, Khulna University of Engineering and Technology (KUET), Khulna, 9203, Bangladesh

    Mamun Jamal, Sumon Chakrabarty & Mohammad A. Yousuf

  2. Micro-Nano Systems Centre, Tyndall National Institute, University College Cork, Dyke Parade, Lee Maltings, Cork, T12 R5CP, Ireland

    Han Shao & Kafil M. Razeeb

  3. Department of Chemistry, University College Cork, Cork, T12 YN60, Ireland

    Han Shao & David McNulty

  4. Department of Mechanical System Engineering, Graduate School of Science and Engineering, Yamagata University, Jonan 4-3-16, Yonezawa, Yamagata, 992-8510, Japan

    Hidemitsu Furukawa & Ajit Khosla

Authors
  1. Mamun Jamal
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  2. Sumon Chakrabarty
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  3. Han Shao
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  4. David McNulty
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  5. Mohammad A. Yousuf
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  6. Hidemitsu Furukawa
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  7. Ajit Khosla
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  8. Kafil M. Razeeb
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Correspondence to Mamun Jamal or Kafil M. Razeeb.

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Jamal, M., Chakrabarty, S., Shao, H. et al. A non enzymatic glutamate sensor based on nickel oxide nanoparticle. Microsyst Technol 24, 4217–4223 (2018). https://doi.org/10.1007/s00542-018-3724-6

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  • DOI: https://doi.org/10.1007/s00542-018-3724-6

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