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Effects of intravenous injection of indocyanine green on the oxygen reserve index (ORi™)

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Abstract

Purpose

The oxygen reserve index (ORi™) is a parameter used for the noninvasive evaluation of arterial partial pressure of oxygen (PaO2), specifically in the 100–200 mmHg range. We aimed to report on the impact of indocyanine green (ICG) on the ORi™.

Methods

In this study, we retrospectively examined patients who underwent neurosurgery between April and July 2019 and assessed the impact of ICG on ORi™. We excluded patients who did not use ICG or who were not examined for ORi™. The dose and timing of ICG administration were determined by a neurosurgeon. The changes in ORi™ were measured for up to 30 min.

Results

We analyzed ten patients and found that the ORi™ increased to 1.00 in all of them. The median time for ORi ™ to rise to 1.00 after ICG administration was 2 min (range 1–4). After rising to 1.00, ORi ™ decreased and took 27 min to return to the pre-dose value.

Conclusion

It is important to consider the initial rapid increase and subsequent slow decrease in ORi™ when using ICG during surgery.

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Acknowledgements

We would like to thank Editage (www.editage.com) for English language editing.

Funding

The authors have no sources of funding to declare for this manuscript.

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Authors and Affiliations

  1. Department of Anesthesiology, National Hospital Organization Higashihiroshima Medical Center, 513, Saijocho Jike, Higashihiroshima-shi, Hiroshima, Japan

    Hiroshi Kondo, Ayako Kobatake, Yukiko Nao, Ken Hashimoto & Keio Nakatani

  2. Department of Anesthesiology and Critical Care, Hiroshima University, Hiroshima, Japan

    Ryuji Nakamura

Authors
  1. Hiroshi Kondo
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  2. Ryuji Nakamura
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  3. Ayako Kobatake
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  4. Yukiko Nao
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  5. Ken Hashimoto
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  6. Keio Nakatani
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Corresponding author

Correspondence to Hiroshi Kondo.

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Kondo, H., Nakamura, R., Kobatake, A. et al. Effects of intravenous injection of indocyanine green on the oxygen reserve index (ORi™). J Anesth 34, 338–341 (2020). https://doi.org/10.1007/s00540-020-02746-2

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  • DOI: https://doi.org/10.1007/s00540-020-02746-2

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