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Shedding light on the management of acute radiation dermatitis: insight from the MASCC Oncodermatology study group

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Abstract

This paper highlights a collection of eleven recently published manuscripts on the prevention and management of acute radiation dermatitis. These meta-analyses provide additional evidence for the updated clinical practice guidelines by the Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology study group for prevention and management of acute radiation dermatitis. The collection of papers elucidate the currently available evidence on acute radiation dermatitis, highlighting consolidated knowledge, effective treatments, and proposed areas for future clinical trials. Overall, a total of 51 randomized controlled trials were retrieved and included for quantitative analysis of an initial systematic review of literature from 1946 to January 2023. Discussion of the clinical impact of various therapeutic interventions include: antiperspirant and deodorant use, barrier films and dressings, natural and miscellaneous agents, photobiomodulation therapy, topical corticosteroids, topical non-steroidal agents, skin hygiene and washing, as well as StrataXRT and Mepitel film in breast cancer patients. The comprehensive nature of the meta-analyses and their related findings may help reduce the discrepancies in in treatment of acute radiation dermatitis and facilitate consistency of therapeutic interventions employed in clinical practice worldwide.

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Acknowledgements

P.B. is the first and J.R.W. is the senior author. J.R.W. is the Chair of the Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology Study Group. P.B. is a member of the MASCC Oncodermatology Study Group.

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Authors and Affiliations

  1. Department of Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

    Pierluigi Bonomo

  2. Departments of Dermatology & Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 697, Rochester, NY, 14642, USA

    Julie Ryan Wolf

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  1. Pierluigi Bonomo
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Both authors contributed to this paper. The first draft of the manuscript was written by P.B. with subsequent versions edited by J.R.W. and P.B. Both authors approved the final manuscript.

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Correspondence to Julie Ryan Wolf.

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Bonomo, P., Wolf, J.R. Shedding light on the management of acute radiation dermatitis: insight from the MASCC Oncodermatology study group. Support Care Cancer 31, 568 (2023). https://doi.org/10.1007/s00520-023-08011-y

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