Abstract
Purpose
The aim of this systematic review was to investigate the clinical effectiveness of glass ionomer cements (GICs) compared to other restorative materials in the treatment of radiation-related caries.
Methods
Two independent researchers searched literature databases (PubMed, Scopus, Web of Science, Cochrane Library, Lilacs/BBO) and the grey literature to identify clinical trials that compared GICs with other restorative materials for the treatment of radiation-related caries. The clinical criteria considered for the performance of the restorations were based on the parameters of marginal adaptation/anatomical form, secondary caries, retention, and cumulative failures of the restorations. The methodological quality and risk of bias were evaluated using the Cochrane Collaboration tool.
Results
From a total of 511, only four articles fulfilled the inclusion criteria. Conventional GIC restorations presented higher marginal adaptation failures than the resin-modified glass ionomer cements (RM-GICs) and composite restorations in all of the follow-up periods. Secondary caries was not observed in conventional GIC restorations throughout the follow-up periods, in three out of four of the included studies. RM-GICs and composite restorations showed significantly lower cumulative failure rates than conventional GICs at 6-, 12-, and 18-month follow-ups.
Conclusion
Due to insufficient scientific evidence, it was not possible to conclude that GICs are more effective than other restorative materials for the treatment of radiation-related caries.
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Data availability
The data used in this systematic review are publicly available and included in the manuscript.
Code availability
Not applicable.
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Jullyana M. P. Dezanetti, Bruna L. do Nascimento, and Juliana S. R. Orsi performed the systematic review methodology process. Jullyana M. P. Dezanetti and Evelise M. Souza designed the study and wrote the manuscript. All authors discussed the results and commented on the manuscript.
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Dezanetti, J.M.P., Nascimento, B.L., Orsi, J.S.R. et al. Effectiveness of glass ionomer cements in the restorative treatment of radiation-related caries — a systematic review. Support Care Cancer 30, 8667–8678 (2022). https://doi.org/10.1007/s00520-022-07168-2
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DOI: https://doi.org/10.1007/s00520-022-07168-2