Skip to main content
Log in

Early hemodynamic assessment and treatment of elderly patients in the medical ICU

  • geriatrics: at crossroads of medicine
  • Published:
Wiener klinische Wochenschrift Aims and scope Submit manuscript

Summary

Background and objectives

The aim of this retrospective study was to analyze differences in the initial hemodynamic assessment and its impact on the treatment in patients aged 80 years or older compared to younger patients during the first 6 h after admission to the medical intensive care unit (ICU).

Results

We analyzed 615 consecutive patients admitted to the medical ICU of which 124 (20%) were aged 80 years or more. The older group had a significantly higher acute physiology and chronic health evaluation (APACHE II) score, an overall mortality in the ICU and a presence of pre-existing cardiac disease. Both groups did not differ in the presence of shock and shock types on admission. In 57% of older and in 56% of younger patients, transthoracic echocardiography was performed with a higher therapeutic impact in the older patients. Transesophageal echocardiography was performed in 3% of the patients in both groups for specific diagnostic problems. Early reassessment with transthoracic echocardiography was necessary in 5% of the older and in 6% of the younger patients and resulted in a change of the treatment in one third of the patients. Continuous invasive hemodynamic monitoring was used in 11% of the older and in 10% of the younger patients and resulted in a therapeutic change in 71% of the older and in 64% of the younger patients.

Conclusion

Patients aged 80 years or older represent 20% of all admissions to the medical ICU. Once admitted the older patients were similarly hemodynamically assessed as the younger ones with a similar impact on the treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Abbreviations

CCO:

Continuous cardiac output

CO:

Cardiac output

CVC:

Central venous catheter

CVP:

Central venous pressure

EVLW:

Extravascular lung water

GEDV:

Global end-diastolic volume

ICU:

Intensive care unit

ITBV:

Intrathoracic blood volume

IVC:

Inferior vena cava

PAC:

Pulmonary artery catheter

PAOP:

Pulmonary artery occlusion pressure

PiCCO:

Pulse-induced continuous cardiac output

LVEF:

Left ventricular ejection fraction

ScvO2 :

Central venous oxygen saturation

SvO2 :

Mixed venous oxygen saturation

TAPSE:

Tricuspid annular plane systolic excursion

TEE:

Transesophageal echocardiography

TTE:

Transthoracic echocardiography

VTI:

Velocity time integral

References

  1. Bose EL, Hravnak M, Pinsky MR. The interface between monitoring and physiology at the bedside. Crit Care Clin. 2015;31:1–24.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Sevransky J. Clinical assessment of hemodynamically unstable patients. Curr Opin Crit Care. 2009;15:234–8.

    Article  PubMed  PubMed Central  Google Scholar 

  3. AzuRea group, Muller L, Bobbia X, Toumi M, et al. Respiratory variations of inferior vena cava diameter to predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure: need for a cautious use. Crit Care. 2012;16:R188.

    Article  Google Scholar 

  4. Osman D, Ridel C, Ray P, Monnet X, ANguel N, Richard C, Teboul JL. Cardiac filling pressures are not appropriate to predict hemodynamic support to volume challege. Crit Care Med. 2007;35:64–8.

    Article  PubMed  Google Scholar 

  5. Bakker J, Nijsten MWN, Jansen TC. Clinical use of lactate monitoring in critically ill patients. Ann Intensive Care. 2013;3:12.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Reinhart K, Kuhn HJ, Hartog C, Bredle DL. Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill. Intensive Care Med. 2004;30:1572–8.

    Article  PubMed  Google Scholar 

  7. Alhashemi JA, Cecconi M, Hofer C. Cardiac output monitoring: an integrative perspective. Crit Care. 2011;15:214.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Funcke S, Sander M, Goepfert SM, et al. Practice of hemodynamic monitoring and management in German, Austrian, and Swiss intensive care unit: the multicenter cross-sectional ICU-CardioMan Study. Ann Intensive Care. 2016;6:49–58.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Cecconi M, Hofer C, Teboul JL, et al. Fluid challenges in intensive care: the FENICE study A global inception cohort study. Intensive Care Med. 2015;41:1529–37.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Garrouste-Orgeas M, Boumendil A, Pateron D, Aergerter P, Somme D, Simon T, Guidet B. Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: an observational, multicenter, prospective study. Crit Care Med. 2009;37(11):2919–28.

    Article  PubMed  Google Scholar 

  11. Nguyen HL, Saczynski JS, Gore JM, Goldberg RJ. Age and sex differences in duration of prehospital delay in patients with acute myocardial infarction: a systematic review. Circ Cardiovasc Qual Outcomes. 2010;3:82–92.

    Article  PubMed  Google Scholar 

  12. Lerolle N, Trinquart L, Bornstain C, et al. Increased intensity of reatment and decreased mortality in elderly patients in an intensive care unit over a decade. Crit Care Med. 2010;38:59–64.

    Article  PubMed  Google Scholar 

  13. Cecconi M, De Backer D, Antonelli M, et al. Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med. 2014;40:1795–815.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Ihra GC, Lehberger J, Hochrieser H, et al. Development of demographics and outcome of very old critically ill patients admitted to intensive care units. Intensive Care Med. 2012;38:620–6.

    Article  PubMed  Google Scholar 

  15. Nguyen YL, Angus DC, Boumendil A, Guidet B. The challenge of admitting the very elderly to intensive care. Ann Intensive Care. 2011;1:29–36.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Sprung CL, Artigas A, Kesecioglu J, et al. The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly. Crit Care Med. 2012;40:132–8.

    Article  PubMed  Google Scholar 

  17. Brunner-Ziegler S, Heinze G, Ryffel M, Kompatscher M, Slany J, Valentin A. “Oldest old” patients in intensive care: prognosis and therapeutic activity. Wien Klin Wochenschr. 2007;119:14–9.

    Article  PubMed  Google Scholar 

  18. Becker S, Müller J, de Heer G, Braune S, Fuhrmann V, Kluge S. Clinical characteristics and outcome of very elderly patients ≥90 years in intensive care: a retrospective observational study. Ann Intensive Care. 2015;5:53–61.

    Article  PubMed  PubMed Central  Google Scholar 

  19. De Rooij SE, Govers AC, Korevaar JC, Giesbers AW, Levi M, de Jonge E. Cognitive, functional, and quality-of-life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment. J Am Geriatr Soc. 2008;56:816–22.

    Article  PubMed  Google Scholar 

  20. Dawson NV, Connors AF, Speroff T, Kemka A, Shaw P, Arkes HR. Hemodynamic assessment in managing the critically ill: Is physician confidence warranted? Med Decis Making. 1993;13:258–66.

    Article  CAS  PubMed  Google Scholar 

  21. Joseph MX, Disney PJ, Da Costa R, Hutchison SJ. Transthoracic echocardiography to identify or exclude cardiac cause of shock. Chest. 2004;126:1592–7.

    Article  PubMed  Google Scholar 

  22. Poelaert JI, Trouerbach J, De Buyzere M, Everaert J, Colardyn FA. Evaluation of transesophageal echocardiography as a diagnostic and therapeutic aid in a critical care setting. Chest. 1995;107:774–9.

    Article  CAS  PubMed  Google Scholar 

  23. Fuchs JB, Goerge G, Morschel C, Bruch C, Erbel R. Wert der echocardiography auf einer algemeininternistischen intensivstation. Intensivmed Notfallmed. 1997;34:549–55.

    Article  Google Scholar 

  24. Manasia A, Cucu D, Oropello J, DelGiudice R, Hufanda J, Benjamin E. Clinical impact of early goal-directed echocardiography in shock patients performed by non-cardiologist intensivists free to view. Chest. 2005;128:222.

    Article  Google Scholar 

  25. De Backer D. Ultrasonic evaluation of the heart. Curr Opin Crit Care. 2014;20:309–3014.

    Article  PubMed  Google Scholar 

  26. Takala J, Roukonen E, Tenhunen JJ, Parviainen I, Jakob SM. Early non-invasive cardiac output monitoring in hemodynamically unstable patients: A multi-center randomized controlled trial. Crit Care. 2011;15:R148.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Cecconi M, Bennett D. Should we use early less invasive hemodynamic monitoring in unstable ICU patients? Crit Care. 2011;15:173–4.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Marx G, Reinhart K. Venous oximetry. Curr Opin Crit Care. 2006;12:263–8.

    Article  PubMed  Google Scholar 

  29. Hofer CK, Cecconi M, Marx G, della Roca G. Minimally invasive hemodynamic monitoring. Eur J Anesthesiol. 2009;26:996–1002.

    Article  Google Scholar 

  30. Shah MR, Hasselblad V, Stevenson LW, et al. Impact of the pulmonary artery catheter in critically ill patients. JAMA. 2005;294:1664–70.

    Article  CAS  PubMed  Google Scholar 

  31. Chittock DR, Dhingra VK, Ronco JJ, et al. Severity of illness and risk of death associated with pulmonary artery catheter use. Crit Care Med. 2004;32:911–5.

    Article  PubMed  Google Scholar 

  32. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345:1368–77.

    Article  CAS  PubMed  Google Scholar 

  33. Tánczos K, Németh M, Molnár Z. The Multimodal concept of hemodynamic stabilization. Front Public Health. 2014;2:34.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gorazd Voga MD, Ph.D., EDIC.

Ethics declarations

Conflict of interest

G. Voga and L. Gabršček-Parežnik declare that they have no competing interests.

Additional information

Author´s contribution G. Voga prepared the manuscript; L. Gabršček-Parežnik analyzed and collected the data and revised the manuscript.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Voga, G., Gabršček-Parežnik, L. Early hemodynamic assessment and treatment of elderly patients in the medical ICU. Wien Klin Wochenschr 128 (Suppl 7), 505–511 (2016). https://doi.org/10.1007/s00508-016-1131-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00508-016-1131-5

Keywords

Navigation