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The prevalence and clinical importance of incidentally detected noncoronary cardiovascular findings with coronary multidetector CT angiography

Prävalenz und klinische Bedeutung von mittels koronarer Multidetektor CT-Angiographie zufällig entdeckten nicht-koronaren kardiovaskulären Befunden

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Summary

Objective

The purpose of this study was to determine the prevalence and clinical importance of incidental findings of noncoronary cardiac structures and mediastinal great vessels in patients who underwent coronary computed tomography angiography (CCTA).

Methods

The study included 2,096 consecutive patients (1,472 men and 624 women, with a mean age of 55 years). Cardiovascular findings were categorized into three groups according to the clinical importance: group 1 included findings necessitating immediate treatment or intervention; group 2 included findings requiring clinical awareness, follow-up, or further clinical and/or radiological investigations; and group 3 included findings not requiring any follow-up or further tests. We also evaluated whether there was any previous diagnosis of cardiovascular findings.

Results

A total of 174 abnormalities (8.3 %) were detected in 170 patients. Of these abnormalities, 21 findings (12 %) were considered as group 1, 121 (69.5 %) as group 2, and 32 (18.5 %) as group 3. The majority of cardiovascular findings (140 of 174, 80.5 %) were unknown by the reporter during the interpretation of CCTA examinations and regarded as incidental findings.

Conclusion

Noncoronary incidental cardiovascular findings in patients who underwent CCTA are common. It is important to be aware of these findings necessitating immediate treatment or intervention, and follow-up or further investigations, and careful attention must be paid to all the structures included in the images.

Zusammenfassung

Ziel

der Studie war es, die Prävalenz und klinische Bedeutung von zufällig erhobenen Befunden nicht-koronarer kardialer Strukturen und mediastinaler großer Gefäße bei Patienten zu erheben, bei denen eine Koronare Computertomographische Angiographie (KCTA) durchgeführt worden war.

Methodik

Die Studie schloss 2096 konsekutive Patienten (1472 Männer und 624 Frauen – mittleres Alter: 55 Jahre) ein. Die kardiovaskulären Befunde wurden in 3 Gruppen entsprechend ihrer klinischer Bedeutung eingeteilt: Gruppe 1: der Befund machte eine sofortige Behandlung oder Intervention notwendig. Gruppe 2: die Befunde gaben Anlass zu klinischer Achtsamkeit, Kontrolle und/oder weiteren klinischen und/oder radiologischen Untersuchungen. Gruppe 3: die Befunde erforderten keine Kontrollen oder weitere Untersuchungen. Wir untersuchten auch, ob die erhobenen kardiovaskulären Diagnosen vor der Untersuchung schon bekannt waren.

Ergebnisse

Insgesamt wurden 174 Anomalitäten (8,3 %) bei 170 Patienten entdeckt. 21 Befunde (12 %) wurden als der Gruppe 1 zugehörig eingestuft, 121 Befunde (69,5 %) der Gruppe 2 und 32 Befunde (18,5 %) der Gruppe 3. Der Großteil der kardiovaskulären Befunde (140/174; 80,5 %) waren vor der KCTA nicht bekannt und wurden daher als Zufallsbefunde gewertet.

Schlussfolgerungen

Nicht koronare kardiovaskuläre abnorme Befunde sind bei Patienten, bei denen eine KCTA durchgeführt wird, häufig. Es ist wichtig, diese Ergebnisse zu kennen, da solche Befunde eine sofortige Behandlung oder Intervention benötigen können. Bei der Befundung sollten daher alle dargestellten kardiale Strukturen mit großer Achtsamkeit betrachtet werden.

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References

  1. Van Ooijen PM, Dorgelo J, Zijlstra F, Oudkerk M. Detection, visualization and evaluation of anomalous coronary anatomy on 16-slice multidetector-row CT. Eur Radiol. 2004;14:2163–71.

    Article  PubMed  Google Scholar 

  2. Henneman MM, Bax JJ, Schuijf JD, van der Wall EE. Noninvasive visualization of the coronary arteries with multi-slice computed tomography; influence of heart rate on diagnostic accuracy. Int J Cardiovasc Imaging. 2006;22:107–9.

    Article  PubMed  Google Scholar 

  3. Kantarci M, Doganay S, Karcaaltincaba M, Karabulut N, Erol MK, Yalcin A, et al. Clinical situations where coronary CT angiography confers superior diagnostic information in comparison to invasive coronary angiography. Diagn Interv Radiol. 2012. doi:10.4261/1305-3825.DIR.5064-11.1.

  4. Hoey E, Ganeshan A, Nader K, Randhawa K, Watkin R. Cardiac neoplasms and pseudotumors: imaging findings on multidetector CT angiography. Diagn Interv Radiol. 2012;18:67–77.

    PubMed  Google Scholar 

  5. Lehman SJ, Abbara S, Cury RC, Nagurney JT, Hsu J, Goela A, Schlett CL, Dodd JD, Brady TJ, Bamberg F, Hoffmann U. Significance of cardiac computed tomography incidental findings in acute chest pain. Am J Med. 2009;122:543–9.

    Article  PubMed  Google Scholar 

  6. Kirsch J, Araoz PA, Steinberg FB, Fletcher JG, McCollough CH, Williamson EE. Prevalence and significance of incidental extracardiac findings at 64-multidetector coronary CTA. J Thorac Imaging. 2007;22:330–4.

    Article  PubMed  Google Scholar 

  7. Law YM, Huang J, Chen K, Cheah FK, Chua T. Prevalence of significant extracoronary findings on multislice CT coronary angiography examinations and coronary artery calcium scoring examinations. J Med Imaging Radiat Oncol. 2008;52:49–56.

    Article  CAS  PubMed  Google Scholar 

  8. Sundaram B, Patel S, Agarwal P, Kazerooni EA. Anatomy and terminology for the interpretation and reporting of cardiac MDCT: part 2, CT angiography, cardiac function assessment, and noncoronary and extracardiac findings. AJR Am J Roentgenol. 2009;192:584–98.

    Article  PubMed  Google Scholar 

  9. Kim JW, Kang EY, Yong HS, Kim YK, Woo OH, Oh YW, et al. Incidental extracardiac findings at cardiac CT angiography: comparison of prevalence and clinical significance between precontrast low-dose whole thoracic scan and postcontrast retrospective ECG-gated cardiac scan. Int J Cardiovasc Imaging. 2009;25:75–81.

    Article  PubMed  Google Scholar 

  10. Aglan I, Jodocy D, Hiehs S, Soegner P, Frank R, Haberfellner B, et al. Clinical relevance and scope of accidental extracoronary findings in coronary computed tomography angiography: a cardiac versus thoracic FOV study. Eur J Radiol. 2010;74:166–74.

    Article  PubMed  Google Scholar 

  11. Mueller J, Jeudy J, Poston R, White CS. Cardiac CT angiography after coronary bypass surgery: prevalence of incidental findings. AJR Am J Roentgenol. 2007;189:414–9.

    Article  PubMed  Google Scholar 

  12. Jacobs PC, Mali WP, Grobbee DE, van der Graaf Y. Prevalence of incidental findings in computed tomographic screening of the chest: a systematic review. J Comput Assist Tomogr. 2008;32:214–21.

    Article  PubMed  Google Scholar 

  13. Horton KM, Post WS, Blumenthal RS, Fishman EK. Prevalence of significant noncardiac findings on electron-beam computed tomography coronary artery calcium screening examinations. Circulation. 2002;106:532–4.

    Article  PubMed  Google Scholar 

  14. Hunold P, Schmermund A, Seibel RM, Grönemeyer DH, Erbel R. Prevalence and clinical significance of accidental findings in electron-beam tomographic scans for coronary artery calcification. Eur Heart J. 2001;22:1748–58.

    Article  CAS  PubMed  Google Scholar 

  15. Onuma Y, Tanabe K, Nakazawa G, Aoki J, Nakajima H, Ibukuro K, et al. Noncardiac findings in cardiac imaging with multidetector computed tomography. J Am Coll Cardiol. 2006;48:402–6.

    Article  PubMed  Google Scholar 

  16. Haller S, Kaiser C, Buser P, Bongartz G, Bremerich J. Coronary artery imaging with contrast-enhanced MDCT: extracardiac findings. AJR Am J Roentgenol. 2006;187:105–10.

    Article  PubMed  Google Scholar 

  17. Vogel-Claussen J, Li D, Carr J, Liu K, Szklo M, Lima JA, et al. Extracoronary abnormalities on coronary magnetic resonance angiography in the multiethnic study of atherosclerosis study: frequency and clinical significance. J Comput Assist Tomogr. 2009;33:752–4.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Budoff MJ, Fischer H, Gopal A. Incidental findings with cardiac CT evaluation: should we read beyond the heart? Catheter Cardiovasc Interv. 2006;68:965–73.

    Article  PubMed  Google Scholar 

  19. Knickelbine T, Lesser JR, Haas TS, Brandenburg ER, Gleason-Han BK, Flygenring B, et al. Identification of unexpected nonatherosclerotic cardiovascular disease with coronary CT angiography. JACC Cardiovasc Imaging. 2009;2:1085–92.

    Article  PubMed  Google Scholar 

  20. Taylor AJ, Cerqueira M, Hodgson JM, Mark D, Min J, O’Gara P, et al. ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance. J Am Coll Cardiol. 2010;56:1864–94.

    Article  PubMed  Google Scholar 

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The authors declare that there is no conflict of interest and financial relationship.

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Correspondence to Mustafa Koplay MD.

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Erol, C., Koplay, M., Şeker, M. et al. The prevalence and clinical importance of incidentally detected noncoronary cardiovascular findings with coronary multidetector CT angiography. Wien Klin Wochenschr 126, 460–467 (2014). https://doi.org/10.1007/s00508-014-0556-y

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  • DOI: https://doi.org/10.1007/s00508-014-0556-y

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