Abstract
Background
Monitoring proteinuria in patients with kidney disease is of crucial importance given its implications for long-term disease progression and clinical management. Leveraging digital health technology to provide a clinical grade urinalysis result from home holds the potential to greatly enhance the clinical experience and workflows for patients, caregivers, and providers. The goal of this study was to evaluate the acceptability and feasibility of a home-based urinalysis kit using a smartphone application.
Methods
This is a prospective cohort study of children and young adults (5–21 years of age) at a single pediatric center. The study received ethical board approval. Families performed a home urine test using the Healthy.io smartphone app. The app was compared with standard of care of either home dipstick monitoring or urinalysis performed in clinic or a local laboratory. Patient satisfaction was compared between the new app and current practice.
Results
A total of 103 children, 63 (61%) male and median age 10.9 years (inter-quartile range 7.8–14.2), were enrolled. Primary diagnosis included 47 (46%) glomerular disease, 48 (47%) non-glomerular kidney disease, and 8 (8%) kidney transplant recipients. One hundred and one (98%) patients reported being satisfied with the smartphone app compared to 41 (40%) patients who were satisfied with the current practice for urine protein monitoring (p < 0.0001). Positive themes identified included ease of use, convenience, and immediacy and accuracy of results.
Conclusions
The Healthy.io home urine testing app received very high rates of satisfaction among patients and caregivers compared to current practice and holds great potential to enhance patient-centered care.
Graphical abstract
A higher resolution version of the Graphical abstract is available as Supplementary information.
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Funding
Healthy.io provided the urine home kits and technical support for the portal. Additional funding for this project was provided by the Pediatric Center of Excellence in Nephrology (PCEN) at CHOP (P50DK114786).
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Erez, D.L., Derwick, H., Furth, S. et al. Dipping at home: is it better, easier, and more convenient? A feasibility and acceptability study of a novel home urinalysis using a smartphone application. Pediatr Nephrol 38, 139–143 (2023). https://doi.org/10.1007/s00467-022-05556-8
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DOI: https://doi.org/10.1007/s00467-022-05556-8