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Single-centre empirical analysis of double-balloon enteroscopy in the diagnosis and treatment of small bowel diseases: A retrospective study of 466 cases

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Abstract

Background and objective

The diagnosis and treatment of small bowel diseases (SBDs) has always been a challenge. The purpose of this study was to evaluate the value of double-balloon enteroscopy (DBE) in the diagnosis and treatment of small bowel diseases.

Method

The clinical data of 466 patients who underwent double-balloon enteroscopy (DBE) in the Endoscope Center of Gastroenterology Department of the First People's Hospital of Yunnan Province from Jan. 2015 to Dec. 2020 were analysed retrospectively. The factors included age, sex, indications, endoscopic treatment results, pathological results, discharge diagnosis and so on.

Results

A total of 370 patients underwent 466 double-balloon enteroscopies, among whom 274 underwent one examination and 96 received two-way examinations (oral and transanal approaches). Abnormalities were detected in 299 cases, with a detection rate of 80.81% (299/370). The common indications were occult gastrointestinal bleeding (OGIB) (30.8%, 114/370) and abdominal pain (28.3%, 105/370). The diagnosis rates were 64.9% and 77.1%, respectively. The common positive findings included nonspecific inflammation/erosion (60 cases), ulcers (34 cases), diverticulum (32 cases), polyps (26 cases) and Crohn's disease (CD) (24 cases). The common tumours were lymphoma(12 cases), adenocarcinoma(11 cases) and stromal tumour(8 cases). Lymphoma was mostly located in the ileum, while stromal tumours and adenocarcinoma were mostly located in the duodenum and jejunum. The main endoscopic intervention measures were haemostasis and polypectomy, including haemostatic clip, argon plasma coagulation (APC), endoscopic mucosal resection (EMR), endoscopic trap resection, endoscopic foreign body extraction and other operations, without serious complications.

Conclusion

DBE has a high success rate in the diagnosis and treatment of some SBDs, and it is a safe and effective management method.

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Authors and Affiliations

  1. Department of Digestive System, Kunhua Hospital Affiliated to Kunming University of Science and Technology, The First People’s Hospital of Yunnan Province, No. 157 Jinbi Road, Kunming, 650032, Yunnan, China

    Liming Lu, Chao Yang, Tian He, Xuan Bai, Minmin Fan, Yajing Yin, Ping Wan & Hui Tang

  2. Medical School, Kunming University of Science and Technology, No. 727 Jingming South Road, Kunming, 650500, Yunnan, China

    Liming Lu

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  1. Liming Lu
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  2. Chao Yang
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  3. Tian He
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  5. Minmin Fan
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Contributions

Study conception and design (PW, HT); acquisition, analysis and interpretation of data (LL, TH, MF, PW); drafting of the manuscript (LL, CY, XB); critical revision of the manuscript for important intellectual content (LL, YY, PW); study supervision (PW, HT). The article has been approved by all authors to be published.

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Correspondence to Ping Wan or Hui Tang.

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Disclosures

Drs. Liming Lu, Chao Yang, Tian He, Xuan Bai, Minmin Fan, Yajing Yin, Ping Wan and Hui Tang stated that they do not have any conflicts of interest or financial ties to disclose.

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Lu, L., Yang, C., He, T. et al. Single-centre empirical analysis of double-balloon enteroscopy in the diagnosis and treatment of small bowel diseases: A retrospective study of 466 cases. Surg Endosc 36, 7503–7510 (2022). https://doi.org/10.1007/s00464-022-09179-w

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  • DOI: https://doi.org/10.1007/s00464-022-09179-w

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