Abstract
Background
Although peroral endoscopic myotomy (POEM) has emerged as a highly efficacious procedure in the treatment of a variety of esophageal motility disorders, currently no standard pathway for postprocedural care exists. Our study aims to report institutional outcomes in performing POEM as an outpatient procedure with same-day discharge. Additionally, we seek to determine factors associated with admission.
Methods
Demographic, perioperative, and postoperative outcome data of 115 patients who underwent POEM between June 2014 and January 2020 on a same-day discharge pathway were analyzed. Cohorts were compared using the t test, Wilcoxon rank-sum, or chi-square test. Multivariable logistic regression with a manual backward selection method was used to identify factors associated with admission.
Results
Fifty-five patients (48%) were successfully discharged same-day. The most common primary reasons for admission were delay in obtaining an esophagram (25%), intraoperative complication (13.3%), and pain (10%). There were no differences in 30-day ED visit rate (12.7% vs 15.0%, p = 0.725) or 30-day readmission rate (9.1% vs 16.7%, p = 0.373) between patients who were discharged same-day versus patients who were admitted. Patients discharged same-day had fewer intraoperative complications (1 vs 9, p = 0.017), shorter OR time (69 vs 100 min, p < 0.001), and earlier cessation of narcotic use (day 0 vs day 1, p = 0.001). On multivariable analysis, intraoperative complication (p = 0.048) was associated with overnight admission.
Conclusion
Patients did not experience additional morbidity with same-day discharge after POEM. A delay in obtaining an esophagram was the most common reason that patients were admitted and those who suffered an intraoperative complication are more likely to require admission.
Similar content being viewed by others
References
Boeckxstaens GE, Zaninotto G, Richter JE (2014) Achalasia. Lancet 383:83–93. https://doi.org/10.1016/S0140-6736(13)60651-0
Bonatti H, Hinder RA, Klocker J, Neuhauser B, Klaus A, Achem SR, de Vault K (2005) Long-term results of laparoscopic Heller myotomy with partial fundoplication for the treatment of achalasia. Am J Surg 190:883–887. https://doi.org/10.1016/j.amjsurg.2005.08.012
Bessell JR, Lally CJ, Schloithe A, Jamieson GG, Devitt PG, Watson DI (2006) Laparoscopic cardiomyotomy for achalasia: long-term outcoMES. ANZ J Surg 76:558–562. https://doi.org/10.1111/j.1445-2197.2006.03784.x
Cowgill SM, Villadolid D, Boyle R, Al-Saadi S, Ross S, Rosemurgy AS (2009) Laparoscopic Heller myotomy for achalasia: results after 10 years. Surg Endosc 23:2644–2649. https://doi.org/10.1007/s00464-009-0508-1
Yamamura MS (2000) Laparoscopic Heller myotomy and anterior fundoplication for achalasia results in a high degree of patient satisfaction. Arch Surg 135:902. https://doi.org/10.1001/archsurg.135.8.902
Chen X, Li Q, Ji G, Ge X, Zhang X, Zhao X, Miao L (2015) Two-year follow-up for 45 patients with achalasia who underwent peroral endoscopic myotomy. Eur J Cardiothorac Surg 47:890–896. https://doi.org/10.1093/ejcts/ezu320
Inoue H, Sato H, Ikeda H, Onimaru M, Sato C, Minami H, Yokomichi H, Kobayashi Y, Grimes KL, Kudo S (2015) Per-oral endoscopic myotomy: a series of 500 patients. J Am Coll Surg 221:256–264. https://doi.org/10.1016/j.jamcollsurg.2015.03.057
Ramchandani M, Reddy DN, Darisetty S, Kotla R, Chavan R, Kalpala R, Galasso D, Lakhtakia S, Rao GV (2016) Peroral endoscopic myotomy for achalasia cardia: treatment analysis and follow up of over 200 consecutive patients at a single center: POEM for achalasia cardia. Dig Endosc 28:19–26. https://doi.org/10.1111/den.12495
Li Q-L, Wu Q-N, Zhang X-C, Xu M-D, Zhang W, Chen S-Y, Zhong Y-S, Zhang Y-Q, Chen W-F, Qin W-Z, Hu J-W, Cai M-Y, Yao L-Q, Zhou P-H (2018) Outcomes of per-oral endoscopic myotomy for treatment of esophageal achalasia with a median follow-up of 49 months. Gastrointest Endosc 87:1405–1412.e3. https://doi.org/10.1016/j.gie.2017.10.031
Ujiki MB, Yetasook AK, Zapf M, Linn JG, Carbray JM, Denham W (2013) Peroral endoscopic myotomy: a short-term comparison with the standard laparoscopic approach. Surgery 154:893–900. https://doi.org/10.1016/j.surg.2013.04.042
Hungness ES, Teitelbaum EN, Santos BF, Arafat FO, Pandolfino JE, Kahrilas PJ, Soper NJ (2013) Comparison of perioperative outcomes between peroral esophageal myotomy (POEM) and laparoscopic Heller myotomy. J Gastrointest Surg 17:228–235. https://doi.org/10.1007/s11605-012-2030-3
Schaheen LW, Sanchez MV, Luketich JD (2018) Peroral endoscopic myotomy for achalasia. Thorac Surg Clin 28:499–506. https://doi.org/10.1016/j.thorsurg.2018.07.005
El Khoury R, Teitelbaum EN, Sternbach JM, Soper NJ, Harmath CB, Pandolfino JE, Kahrilas PJ, Hungness ES (2016) Evaluation of the need for routine esophagram after peroral endoscopic myotomy (POEM). Surg Endosc 30:2969–2974. https://doi.org/10.1007/s00464-015-4585-z
Sternbach JM, El Khoury R, Teitelbaum EN, Soper NJ, Pandolfino JE, Hungness ES (2015) Early esophagram in per-oral endoscopic myotomy (POEM) for achalasia does not predict long-term outcomes. Surgery 158:1128–1136. https://doi.org/10.1016/j.surg.2015.05.023
Benias PC, Korrapati P, Raphael KL, D’Souza LS, Inamdar S, Trindade AJ, Lee C, Kumbhari V, Sejpal DV, Okolo P, Khashab MA, Miller L, Carr-Locke D (2019) Safety and feasibility of performing peroral endoscopic myotomy as an outpatient procedure with same-day discharge. Gastrointest Endosc. https://doi.org/10.1016/j.gie.2019.04.247
Eckardt VF, Aignherr C, Bernhard G (1992) Predictors of outcome in patients with achalasia treated by pneumatic dilation. Gastroenterology 103:1732–1738. https://doi.org/10.1016/0016-5085(92)91428-7
Gockel I, Junginger T (2007) The Value of Scoring Achalasia: A Comparison of Current Systems and the Impact on Treatment—The Surgeon’s Viewpoint. The American surgeon 73:327–331. https://doi.org/10.1177/000313480707300403
Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJPM, Pandolfino JE, International High Resolution Manometry Working Group (2015) The Chicago classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil 27:160–174. https://doi.org/10.1111/nmo.12477
Ward MA, Gitelis M, Patel L, Vigneswaran Y, Carbray J, Ujiki MB (2017) Outcomes in patients with over 1-year follow-up after peroral endoscopic myotomy (POEM). Surg Endosc 31:1550–1557. https://doi.org/10.1007/s00464-016-5130-4
DeMeester SR (2017) Per-oral endoscopic myotomy for achalasia. J Thorac Dis 9:S130–S134. https://doi.org/10.21037/jtd.2016.09.39
Campagna RAJ, Hungness ES (2018) Treatment of idiopathic achalasia with per-oral esophageal myotomy. Tech Gastrointest Endosc 20:114–119. https://doi.org/10.1016/j.tgie.2018.07.006
Li H, Peng W, Huang S, Ren Y, Peng Y, Li Q, Wu J, Fu X, Tang X (2019) The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review. J Cardiothorac Surg 14:1. https://doi.org/10.1186/s13019-018-0811-9
Haito-Chavez Y, Inoue H, Beard KW, Draganov PV, Ujiki M, Rahden BHA, Desai PN, Pioche M, Hayee B, Haji A, Saxena P, Reavis K, Onimaru M, Balassone V, Nakamura J, Hata Y, Yang D, Pannu D, Abbas A, Perbtani YB, Patel LY, Filser J, Roman S, Rivory J, Mion F, Ponchon T, Perretta S, Wong V, Maselli R, Ngamruengphong S, Chen Y-I, Bukhari M, Hajiyeva G, Ismail A, Pieratti R, Kumbhari V, Galdos-Cardenas G, Repici A, Khashab MA (2017) Comprehensive analysis of adverse events associated with per oral endoscopic myotomy in 1826 patients: an international multicenter study. Am J Gastroenterol 112:1267–1276. https://doi.org/10.1038/ajg.2017.139
Zhang X, Modayil RJ, Friedel D, Gurram KC, Brathwaite CE, Taylor SI, Kollarus MM, Modayil S, Halwan B, Grendell JH, Stavropoulos SN (2018) Per-oral endoscopic myotomy in patients with or without prior Heller’s myotomy: comparing long-term outcomes in a large U.S. single-center cohort (with videos). Gastrointest Endosc 87:972–985. https://doi.org/10.1016/j.gie.2017.10.039
Werner YB, von Renteln D, Noder T, Schachschal G, Denzer UW, Groth S, Nast JF, Kersten JF, Petzoldt M, Adam G, Mann O, Repici A, Hassan C, Rösch T (2017) Early adverse events of per-oral endoscopic myotomy. Gastrointest Endosc 85:708–718.e2. https://doi.org/10.1016/j.gie.2016.08.033
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Disclosures
Drs Linn, Haggerty, and Ujiki receive payment for lectures from Gore. Dr Haggerty is a paid consultant to Medtronic. Dr Ujiki is a board member for Boston Scientific, is a paid consultant for Olympus and Cook, and receives payment for lectures from Medtronic and Erbe. Drs Attaar, Denham, Su, Wong, and Kristine Kuchta have no conflicts of interest or financial ties to disclose.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Attaar, M., Su, B., Wong, H.J. et al. Factors associated with admission after implementation of a same-day discharge pathway in patients undergoing peroral endoscopic myotomy (POEM). Surg Endosc 35, 3971–3980 (2021). https://doi.org/10.1007/s00464-020-07866-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00464-020-07866-0