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Olfactory subsystems associated with the necklace glomeruli in rodents

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Abstract

The necklace glomeruli are a loosely defined group of glomeruli encircling the caudal main olfactory bulb in rodents. Initially defined by the expression of various immunohistochemical markers, they are now better understood in the context of the specialized chemosensory neurons of the main olfactory epithelium and Grueneberg ganglion that innervate them. It has become clear that the necklace region of the rodent main olfactory bulb is composed of multiple distinct groups of glomeruli, defined at least in part by their afferent inputs. In this review, we will explore the necklace glomeruli and the chemosensory neurons that innervate them.

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Funding

This work was supported by grants from the National Institute on Deafness and Other Communication Disorders: R01 DC005633 and T32 DC015994.

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Authors and Affiliations

  1. Department of Pharmacology and Therapeutics, University of Florida College of Medicine, PO Box 100267, Gainesville, FL, 32610, USA

    Arthur D. Zimmerman & Steven D. Munger

  2. Center for Smell and Taste, University of Florida, PO Box 100127, Gainesville, FL, 32610, USA

    Arthur D. Zimmerman & Steven D. Munger

  3. Training Program in Chemosensory Science, University of Florida, PO Box 100127, Gainesville, FL, 32610, USA

    Arthur D. Zimmerman & Steven D. Munger

  4. Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Florida College of Medicine, PO Box 100266, Gainesville, FL, 32610, USA

    Steven D. Munger

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  1. Arthur D. Zimmerman
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Correspondence to Steven D. Munger.

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Zimmerman, A.D., Munger, S.D. Olfactory subsystems associated with the necklace glomeruli in rodents. Cell Tissue Res 383, 549–557 (2021). https://doi.org/10.1007/s00441-020-03388-2

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