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Neuro-regenerative potential of dental stem cells: a concise review

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Abstract

This review will summarize the research information regarding the regenerative potential of dental stem cells for the treatment of neurodegenerative disorders. As compared to existing treatment modalities, the stem cell therapy seems promising, and accumulating evidences about the differentiation of stem cells into various lineages are proving it. The incidence of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, stroke, and peripheral neuropathy is increasing due to the rise in life expectancies of people which have put a huge burden on economies. Finding a promising treatment could benefit not only the patients but also the communities. Dental stem cells hold a great potential to differentiate into neuronal cells. Many studies have reported the differentiation potential of the dental stem cells with the presence of neuronal lineage markers. In this review, we conferred how the use of dental stem cells can benefit the above-mentioned bedridden diseases.

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The sources for the information discussed in this review can be obtained from the papers cited in the references.

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Acknowledgments

This work was supported by Cell Therapy Center-The university of Jordan.

Funding

This study is supported by Cell Therapy Center-The University of Jordan.

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Authors and Affiliations

  1. Department of Pharmacology and Biomedical Sciences, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan

    Duaa Abuarqoub

  2. Cell Therapy Center, The University of Jordan, Amman, Jordan

    Duaa Abuarqoub, Nazneen Aslam, Hanan Jafar & Abdalla Awidi

  3. School of Medicine, The University of Jordan, Amman, Jordan

    Bayan Almajali, Leen Shajrawi, Hanan Jafar & Abdalla Awidi

Authors
  1. Duaa Abuarqoub
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  2. Nazneen Aslam
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  3. Bayan Almajali
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  4. Leen Shajrawi
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  5. Hanan Jafar
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  6. Abdalla Awidi
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Correspondence to Duaa Abuarqoub or Abdalla Awidi.

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Abuarqoub, D., Aslam, N., Almajali, B. et al. Neuro-regenerative potential of dental stem cells: a concise review. Cell Tissue Res 382, 267–279 (2020). https://doi.org/10.1007/s00441-020-03255-0

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