Abstract
Tumor immunotherapy has become an important means of tumor therapy by enhancing the immune response and triggering the activation of immune cells. However, currently, only a small number of patients respond to immunotherapy alone, and patients may experience immune-related adverse events (irAEs) during the course of treatment. Sonodynamic therapy (SDT) can produce cytotoxic substances to tumor tissue, induce apoptosis and enhance immunity. SDT combined with immunotherapy is considered a promising strategy for cancer treatment. In this mini review, we summarize the role of SDT in immunotherapy in recent years, including the application of SDT-triggered immunotherapy and the combination of SDT and immunotherapy.
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Copyright 2021, American Chemical Society
Copyright 2021, American Chemical Society
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This work was supported by the Department of Science and Technology of Jilin Province (Grant No. 20190303140SF), the Department of Finance of Jilin Province (Grant No. 3D5206055430).
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All authors contributed to the study’s conception and design. Hui Wang contributed to the study’s conception and design. Guo-Qing Sui and Zhi-Xia Sun reviewed and edited the manuscript. Yang Wang, Zong-Hua Yue and Han-Yu Zhang performed the literature search and data analysis. The first draft of the manuscript was written by Jia-Rui Du and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Du, JR., Wang, Y., Yue, ZH. et al. Recent advances in sonodynamic immunotherapy. J Cancer Res Clin Oncol 149, 1645–1656 (2023). https://doi.org/10.1007/s00432-022-04190-z
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DOI: https://doi.org/10.1007/s00432-022-04190-z