Abstract
The aim of this study was to investigate functional connectivity between right and left insulae in the human brain. We studied a patient with implanted depth electrodes for epilepsy surgery evaluation with stereotactically placed symmetric depth electrodes in both insulae. Bipolar 1 Hz electrical stimulation of the right and left posterior short gyri in the anterior insula evoked responses in the contralateral insular structures. These responses showed a latency of 8–24 ms. This report demonstrates for the first time bi-directional homotopic and heterotopic functional connectivity between right and left anterior insulae. The short latency of the evoked responses suggests mono- or oligo-synaptic connections, most likely via the corpus callosum.
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Lacuey, N., Zonjy, B., Kahriman, E.S. et al. Homotopic reciprocal functional connectivity between anterior human insulae. Brain Struct Funct 221, 2695–2701 (2016). https://doi.org/10.1007/s00429-015-1065-0
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DOI: https://doi.org/10.1007/s00429-015-1065-0