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Ultrasound-guided erector spinae plane block for postoperative analgesia in Chinese patients undergoing laparoscopic cholecystectomy: a double-blind randomized controlled trial

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Abstract

Purpose

Pain management after laparoscopic cholecystectomy (LC) is a main concern for Chinese clinicians. This study aims to explore the effect of erector spinae plane block (ESPB) on the postoperative analgesia of patients undergoing LC in China.

Methods

In this randomized controlled trial (RCT), 220 patients were randomized into the ESPB group and control group. Patients in the ESPB group received a bilateral ESPB, and patients in the control group were injected saline. Lornoxicam (0.08 mg/mL, 100 mL) was used as routine analgesia for both groups after the surgery. Visual analog scale (VAS) score at rest state at 12 h postoperative was the primary outcome and divided into no pain, mild pain, moderate pain, and severe pain.

Results

Finally, 197 patients were included for analysis. At postoperative 12 h, ESPB group observed less patients with moderate pain (0% vs. 8.91%) and severe pain (0% vs. 0.99%) than the control group (P < 0.001). Moreover, ESPB group found less dose of additional sufentanil (5.55 ± 1.37 μg vs. 10.67 ± 5.05 μg), less requirement for rescue analgesia (13.54% vs. 31.68%), earlier first time to leave bed (10 h vs. 18 h), and earlier first exhaust time (17.5 h vs. 25 h), less adverse reactions (5.21% vs. 17.82%), and higher satisfaction degree (78.13% vs. 31.68%) (all P < 0.05).

Conclusions

ESPB was followed by better postoperative analgesia and less opioid consumption.

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Authors and Affiliations

  1. Department of Anesthesiology, People’s Hospital of Leshan, Leshan, 614000, People’s Republic of China

    Heng Lu, Wei Ye & Zhaohua Zhou

  2. Department of Hepatopancreatobiliary Surgery, People’s Hospital of Leshan, Leshan, 614000, People’s Republic of China

    Qingyun Xie & Zehua Lei

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  1. Heng Lu
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Contributions

Study conception and design: Heng Lu, Zehua Lei; acquisition of data: Qingyun Xie, Wei Ye, and Zhaohua Zhou; analysis and interpretation of data: Qingyun Xie, Wei Ye, and Zhaohua Zhou; drafting of manuscript: Heng Lu and Zehua Lei; critical revision of manuscript: Zehua Lei.

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Correspondence to Zehua Lei.

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Supplementary figure 1

Patients in the lateral recumbent position, skin disinfection, and laying the sterile cloth (A), performing ESPB on B-ultrasound (B), B-ultrasound image of erector spinae plane before injection (C), B-ultrasound image of erector spinae plane after injection (D), and completion of the block (E). (PNG 627 kb)

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Lu, H., Xie, Q., Ye, W. et al. Ultrasound-guided erector spinae plane block for postoperative analgesia in Chinese patients undergoing laparoscopic cholecystectomy: a double-blind randomized controlled trial. Langenbecks Arch Surg 408, 111 (2023). https://doi.org/10.1007/s00423-023-02834-3

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