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Predictability comparison of sizing parameters for postoperative vault after implantable Collamer lens implantation

  • Refractive Surgery
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Abstract

Purpose

This study aims to assess the accuracy of three parameters (white-to-white distance [WTW], angle-to-angle [ATA], and sulcus-to-sulcus [STS]) in predicting postoperative vault and to formulate an optimized predictive model.

Methods

In this retrospective study, a cohort of 465 patients (comprising 769 eyes) who underwent the implantation of the V4c implantable Collamer lens with a central port (ICL) for myopia correction was examined. Least absolute shrinkage and selection operator (LASSO) regression and classification models were used to predict postoperative vault. The influences of WTW, ATA, and STS on predicting the postoperative vault and ICL size were analyzed and compared.

Results

The dataset was randomly divided into training (80%) and test (20%) sets, with no significant differences observed between them. The screened variables included only seven variables which conferred the largest signal in the model, namely, lens thickness (LT, estimated coefficients for logistic least absolute shrinkage of −0.20), STS (−0.04), size (0.08), flat K (−0.006), anterior chamber depth (0.15), spherical error (−0.006), and cylindrical error (−0.0008). The optimal prediction model depended on STS (R2=0.419, RMSE=0.139), whereas the least effective prediction model relied on WTW (R2=0.395, RMSE=0.142). In the classified prediction models of the vault, classification prediction of the vault based on STS exhibited superior accuracy compared to ATA or WTW.

Conclusions

This study compared the capabilities of WTW, ATA, and STS in predicting postoperative vault, demonstrating that STS exhibits a stronger correlation than the other two parameters.

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Acknowledgements

The authors would like to express their deepest gratitude to all the participants in this study; all the hospital staff, for the coordination and logistic arrangements of this study.

Funding

Supported in part by the State administration of traditional Chinese medicine Science and Technology Department-Zhejiang Provincial Administration of Traditional Chinese Medicine Co-construction Science and Technology Plan under Grant (No. GZY-ZJ-KJ-23086), the Science and Technology Program of Traditional Chinese Medicine in Zhejiang Province (No. 2024ZL617), and the Science and Technology Plan Project of Wenzhou Science and Technology Bureau (No. Y2023809).

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Authors and Affiliations

Authors

Contributions

YF.Y. provided the concept and designed this study. J.Z. and FF.L. completed data collection. FF.L. did analysis and interpretation. J.Z. and SY.J. wrote the manuscript. SQ.W., Q.D., G.Y., FJ.B., D.C., XY.Z., and YF.Y. provided critical revision of the manuscript.

Corresponding author

Correspondence to Yu-Feng Ye.

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Ethical approval

The study followed the tenets of the Declaration of Helsinki and was approved by the Ethics Committee of the Eye Hospital of Wenzhou Medical University (H2023-032-K-30). Written informed consent was obtained from each participant.

Conflict of interest

The authors declare no competing interests.

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Zhu, J., Li, FF., Jiang, SY. et al. Predictability comparison of sizing parameters for postoperative vault after implantable Collamer lens implantation. Graefes Arch Clin Exp Ophthalmol (2024). https://doi.org/10.1007/s00417-024-06408-x

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  • DOI: https://doi.org/10.1007/s00417-024-06408-x

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