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Changes in accommodation dynamics after alcohol consumption, for two different doses

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Abstract

Purpose

The purpose of this work was to evaluate possible changes in accommodation dynamics caused by the intake of different doses of alcohol.

Methods

A total of 20 emmetropic subjects took part in the study. This involved a baseline session, a session after consuming 300 ml of red wine, and another after consuming 450 ml of the same wine. The accommodation dynamics were characterized for two target vergences (2.5D and 5.0D) using the Grand Seiko WAM-5500 autorefractor, which provided the accommodation and disaccommodation variables. The accommodative facility was measured using flippers of ± 2.00 D.

Results

The mean accommodation velocities and velocity peaks were significantly lower after consuming alcohol for the higher intake, particularly for 5.0D (p < 0.05). The response time was significantly higher only for the high-intake condition for 5.0D (p < 0.05). The accommodative microfluctuations were significantly higher for both target vergences for the high-intake condition (p < 0.05). The accommodative facility was significantly impaired in both intake conditions (p < 0.05). The breath alcohol content (BrAC) was correlated with the deterioration of some variables: the accommodative facility (ρ = 0.490), and the velocity peak for 2.5D (ρ = 0.349) and 5.0D (ρ = 0.387).

Conclusions

Alcohol intake affects accommodation dynamics, causing deterioration in the mean velocity, velocity peak, response time, accommodative microfluctuations, and accommodative facility, especially for the target vergence of 5.0D and high alcohol dosages.

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Availability of data and materials

Available from the corresponding author on reasonable request.

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Acknowledgments

We thank Local Police of Granada city (Granada, Spain) and Dräger Iberia (Madrid, Spain) for lending us the breath analyzer, and Pago de Almaraes wineries for providing us with the wine used in the study. We also thank Trágora SCA for reviewing the English version of the manuscript.

Funding

This research was supported by the Ministry of Economy and Competitiveness (Spain) and European Regional Development Fund (ERDF) (FIS2017-85058-R).

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Authors and Affiliations

  1. Department of Optics, Laboratory of Vision Sciences and Applications, University of Granada, Granada, Spain

    Miriam Casares-López, José J. Castro-Torres, Sonia Ortiz-Peregrina, Carolina Ortiz & Rosario G. Anera

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  1. Miriam Casares-López
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  2. José J. Castro-Torres
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  3. Sonia Ortiz-Peregrina
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Contributions

MCL contributed on the design of the study, acquisition and interpretation of data and drafting the article. JJCT contributed on the conception and design of the study, drafting the article and revising and approving the version to be published. SOP carried out the acquisition and interpretation of data and drafted the article. COH carried out the interpretation of data, revising, and approving the version to be published. RGA contributed on the conception of the study and revising the article and approving the version to be published, and was responsible of the funding for this study.

Corresponding author

Correspondence to José J. Castro-Torres.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval and informed consent

Before starting the experiment, the participants gave their informed consent in accordance with the Helsinki declaration (World Medical Declaration of Helsinki, 2001). All the methods and procedures used in the study were approved by the University of Granada Human Research Ethics Committee (Approval number: 921/CEIH/2019).

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Casares-López, M., Castro-Torres, J.J., Ortiz-Peregrina, S. et al. Changes in accommodation dynamics after alcohol consumption, for two different doses. Graefes Arch Clin Exp Ophthalmol 259, 919–928 (2021). https://doi.org/10.1007/s00417-020-04978-0

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