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Changes in choroidal vascular parameters following pan-retinal photocoagulation using swept-source optical coherence tomography

  • Retinal Disorders
  • Published:
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Abstract

Background

To assess the effect of pan-retinal photocoagulation (PRP) on choroidal vascular parameters in eyes with advanced diabetic retinopathy (DR).

Methods

Forty patients (65 eyes) with severe nonproliferative DR or proliferative DR who underwent PRP were included. Changes in choroidal vascular parameters were assessed at 3, 6, and 12 months after PRP by using swept-source optical coherence tomography (OCT) and OCT angiography and were compared with baseline values.

Results

Choroidal vascularity index (CVI) significantly decreased from 66.27% ± 1.55% at baseline to 65.85% ± 1.61%, 65.77% ± 1.29%, and 65.74% ± 1.60% at 3, 6, and 12 months after PRP, respectively. The ratio of luminal area to stromal area (L/S ratio) also significantly decreased from 1.98 ± 0.15 at baseline to 1.94 ± 0.14, 1.95 ± 0.13, and 1.93 ± 0.14 at 3, 6, and 12 months after PRP, respectively. The subfoveal choroidal thickness (SFCT) similarly showed a significant decrease from 319.50 ± 56.64 μm at baseline to 299. 07 ± 51.14 μm, 294.70 ± 58.96 μm, and 280.93 ± 53.57 μm at 3, 6, and 12 months after PRP, respectively. However, the choriocapillaris vessel density in both the fovea and parafovea showed no significant differences following PRP.

Conclusion

Eyes with advanced DR showed a significant reduction in CVI, L/S ratio, and SFCT over 12 months after PRP treatment.

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Funding

This work was supported by the National Research Foundation of Korea (NRF-2015R1C1A1A01054285; NRF-2019R1H1A1035593) by the Ministry of Science, Information & Communication Technology (ICT), and Future Planning.

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Authors and Affiliations

  1. Department of Ophthalmology, College of Medicine, Chung-Ang University Hospital, 102 Heukseok-ro, Dongjak-gu, Seoul, #06974, South Korea

    Jee Taek Kim & Nari Park

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  1. Jee Taek Kim
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  2. Nari Park
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Correspondence to Jee Taek Kim.

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Conflict of interest

Author JT Kim declares that he has no conflict of interest. Author N Park declares that she has no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Chung-Ang University Hospital, Seoul, South Korea and with the 1964 Helsinki declaration.

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Informed consent was obtained from all individual participants included in the study.

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This study was presented as a e-poster at the 120th annual meeting of the Korean Ophthalmological Society (02-04 Nov), Seoul, Korea.

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Kim, J.T., Park, N. Changes in choroidal vascular parameters following pan-retinal photocoagulation using swept-source optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 258, 39–47 (2020). https://doi.org/10.1007/s00417-019-04475-z

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  • DOI: https://doi.org/10.1007/s00417-019-04475-z

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