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Bilateral lateral rectus recession versus unilateral recession resection for basic intermittent exotropia: a meta-analysis

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Abstract

Objective

To compare the outcomes between bilateral lateral rectus recession (BLR) and unilateral recession resection (R&R) procedures in the treatment of basic intermittent exotropia.

Methods

Databases from Medline, Embase, Web of Science and the Cochrane Register of Controlled Trials were searched prior to June 2, 2017. From these searches, three eligible randomized studies and three retrospective cohort trials, which compared conventional BLR versus R&R procedure were identified. Differences observed between these two interventions (BLR versus R&R) were expressed as odds ratio (OR) and 95% confidence intervals (CI). The data on rates of success, recurrence, and overcorrection were pooled and analyzed using a random-effects model.

Results

Our findings, as generated from the pooled estimates, suggested that success rates for the R&R procedure were significantly greater than that of BLR (OR, 0.50; 95% CI, 0.31–0.79; P = 0.003) and patients subjected to the BLR procedure were more likely to be recurrent (OR, 2.44; 95% CI, 1.17–5.10; P = 0.02). No statistically significant differences in the combined results for overcorrection rates were present between the BLR and R&R procedures (OR, 0.85; 95% CI, 0.32–2.28; P = 0.75).

Conclusion

The overall findings from this meta-analysis indicated that the conventional R&R procedure is associated with higher success rates and lower recurrence rates in patients with basic intermittent exotropia.

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Contributors

YS and JC conceived the study. YS and JC designed and performed the searches. YS and TZ conducted data extraction, appraisal, and synthesis. YS and JC wrote the manuscript. All authors participated in discussions about eligibility and quality of the included studies, critically reviewed and approved the final version of the manuscript.

Funding

Supported by grants from Guangdong Provincial Scientific Technological Research Fund, China (no. 2014A020209031). The sponsor had no role in the design or conduct of this research.

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Authors and Affiliations

  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China

    Yuan Sun, Ting Zhang & Jingchang Chen

  2. Department of Ophthalmology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China

    Yuan Sun

Authors
  1. Yuan Sun
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  2. Ting Zhang
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  3. Jingchang Chen
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Correspondence to Jingchang Chen.

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The authors declare that they have no conflict of interest.

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For this type of study formal consent is not required.

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This article does not contain any studies with human participants performed by any of the authors.

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Sun, Y., Zhang, T. & Chen, J. Bilateral lateral rectus recession versus unilateral recession resection for basic intermittent exotropia: a meta-analysis. Graefes Arch Clin Exp Ophthalmol 256, 451–458 (2018). https://doi.org/10.1007/s00417-018-3912-1

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  • DOI: https://doi.org/10.1007/s00417-018-3912-1

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