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Macular retinoschisis in eyes with glaucomatous optic neuropathy: Vitrectomy and natural course

  • Retinal Disorders
  • Published:
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Abstract

Purpose

Our purpose was to determine the effectiveness of vitrectomy in resolving the macular retinoschisis in an eye with glaucomatous optic neuropathy and also to determine the natural course of macular retinoschisis.

Methods

This was a retrospective case series of patients who were diagnosed with macular retinoschisis and glaucomatous optic neuropathy. Fourteen eyes of 13 patients were studied. Patients with high myopia, vitreomacular traction syndrome, and the pit macular syndrome were excluded.

Results

There were three men and ten women, and 12 had unilateral and one had bilateral macular retinoschisis. Vitrectomy was performed for a serous retinal detachment, macular hole, or severe visual loss in five eyes. The mean follow-up time was 68.8 months in these five eyes, and the macular retinoschisis was resolved and the best-corrected visual acuity (BCVA) at the final visit was significantly improved in all eyes (P = 0.007). However, two of these fiv e eyes developed a macular hole and required a second vitrectomy. Of the nine eyes without treatment with a mean follow-up time of 29.0 months, the BCVA at the final visit remained unchanged from the baseline BCVA in all eyes. The macular retinoschisis was resolved or reduced in three eyes without treatment.

Conclusions

Vitrectomy was effective for the resolution of macular retinoschisis in eyes with glaucomatous optic neuropathy and serous retinal detachment or macular hole or severe reduction of the BCVA. Macular retinoschisis can be resolved without a reduction of the BCVA in some cases without treatment.

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Acknowledgments

The authors thank Professor Yoshinori Mitamura, Dr. Yoshifumi Okamoto, and Dr. Eiichi Yukawa for helpful advice and data collection, and Professor Emeritus Duco Hamasaki of the Bascom Palmer Eye Institute for discussions and manuscript revision. All members became a part of Japan Clinical Retina Study (J-CREST) group and researched.

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Authors and Affiliations

  1. Department of Ophthalmology, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan

    Tadanobu Yoshikawa & Nahoko Ogata

  2. Department of Ophthalmology, Tokushima University School of Medicine, Tokushima, Japan

    Chihiro Yamanaka

  3. Department of Ophthalmology, Sapporo City General Hospital, Sapporo, Japan

    Takamasa Kinoshita

  4. Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan

    Shohei Morikawa

Authors
  1. Tadanobu Yoshikawa
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  2. Chihiro Yamanaka
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  3. Takamasa Kinoshita
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  4. Shohei Morikawa
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  5. Nahoko Ogata
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Corresponding author

Correspondence to Tadanobu Yoshikawa.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Yoshikawa, T., Yamanaka, C., Kinoshita, T. et al. Macular retinoschisis in eyes with glaucomatous optic neuropathy: Vitrectomy and natural course. Graefes Arch Clin Exp Ophthalmol 256, 281–288 (2018). https://doi.org/10.1007/s00417-017-3855-y

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  • DOI: https://doi.org/10.1007/s00417-017-3855-y

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