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The effectiveness of vitrectomy for diffuse diabetic macular edema may depend on its preoperative optical coherence tomography pattern

  • Retinal Disorders
  • Published:
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Abstract

Background

To investigate the effectiveness of vitrectomy for diffuse diabetic macular edema (DDME) and its dependence on optical coherence tomography (OCT) findings.

Methods

The records of 65 patients and 81 eyes who received vitrectomy for DDME and followed up for at least 6 months were retrospectively reviewed. All eyes were classified according to their morphological characteristics on OCT including sponge-like diffuse retinal thickening (SDRT: n = 13), cystoid macular edema (CME: n = 42), serous retinal detachment (SRD: n = 13), and the combination of all morphological characteristics (FULL: n = 13). The best-corrected visual acuity (BCVA) and spectral domain OCT were investigated preoperatively and at 1, 3, and 6 months postoperatively.

Results

At six months after surgery, BCVA in logMAR units was significantly improved in all groups except the SDRT group. The improvement was −0.04 ± 0.20 in the SDRT group (P = 0.504), −0.16 ± 0.24 in the CME group (P < 0.01), −0.32 ± 0.32 in the SRD group (P < 0.01), and −0.26 ± 0.19 in the FULL group (P < 0.01), and significantly better in eyes with subretinal fluid (SRF; the SRD and FULL groups) than in eyes without SRF (the SDRT and CME groups, P = 0.003).

Conclusions

Vitrectomy can be a useful treatment option for DDME, particularly for eyes with SRF.

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Acknowledgments

The authors have no proprietary interest in any aspect of this study. Supported in part by a grant from the Shiga University of Medical Science.

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Authors and Affiliations

  1. Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan

    Yusuke Ichiyama, Osamu Sawada, Masato Fujikawa, Hajime Kawamura & Masahito Ohji

  2. Soseikai General Hospital, Kyoto, 612-8473, Japan

    Takamasa Mori

Authors
  1. Yusuke Ichiyama
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  2. Osamu Sawada
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  3. Takamasa Mori
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  4. Masato Fujikawa
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  5. Hajime Kawamura
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  6. Masahito Ohji
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Correspondence to Yusuke Ichiyama.

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All authors certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

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Ichiyama, Y., Sawada, O., Mori, T. et al. The effectiveness of vitrectomy for diffuse diabetic macular edema may depend on its preoperative optical coherence tomography pattern. Graefes Arch Clin Exp Ophthalmol 254, 1545–1551 (2016). https://doi.org/10.1007/s00417-015-3251-4

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  • DOI: https://doi.org/10.1007/s00417-015-3251-4

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