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A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration

  • Glaucoma
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Abstract

Background

To evaluate the potential of lowering intraocular pressure in pseudoexfoliation glaucoma with combined phacoemulsification, Trabectome, and trabecular aspiration (triple procedure) compared to phacoemulsification and trabecular aspiration alone.

Methods

Using a case-matched retrospective study design, 30 patients were included into each group. The main outcome measures were the reduction of intraocular pressure and medication score at the end of follow-up. Clinical data were collected from the patients’ medical records.

Results

Mean follow-up was 15 months in both groups. Intraocular pressure decreased from 25.3 ± 6.3 mmHg to 14.4 ± 3.7 mmHg (p < 0.0001) in the triple procedure group and from 25.3 ± 4.2 mmHg to 18.1 ± 4.2 mmHg (p < 0.0001) in the control group. The medication score was lowered from 3.4 ± 1.7 to 2.1 ± 1.2 (p = 0.0017) in the triple procedure group and from 3.8 ± 1.8 to 2.3 ± 1.5 (p < 0.008) in the control group. The reduction of intraocular pressure was higher (p < 0.004) in the triple procedure group (38.4 ± 17.3 %) compared to the control group (26.8 ± 19.6 %) The reduction of the medication score did not differ significantly.

Conclusions

The triple procedure is more effective in lowering intraocular pressure compared to phacoemulsification and trabecular aspiration alone in pseudoexfoliation glaucoma.

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Financial disclosure

The authors have no proprietary or commercial interests in any materials discussed in this article.

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Authors and Affiliations

  1. Department of Ophthalmology, St. Martinus-Krankenhaus, Gladbacher Str. 26, 40219, Düsseldorf, Germany

    Randolf A. Widder, Pia Kühnrich & Klaus-Dieter Lemmen

  2. Department of Ophthalmology, University of Cologne, Cologne, Germany

    Randolf A. Widder, André Rosentreter, Claus Cursiefen & Thomas S. Dietlein

  3. Department of Ophthalmology, University of Freiburg, Freiburg, Germany

    Jens F Jordan

  4. Augenzentrum Tölzer Land, Bad Tölz, Germany

    Sven Dinslage

Authors
  1. Randolf A. Widder
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  2. Sven Dinslage
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  3. André Rosentreter
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  4. Jens F Jordan
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  5. Pia Kühnrich
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  6. Claus Cursiefen
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  7. Klaus-Dieter Lemmen
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  8. Thomas S. Dietlein
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Correspondence to Randolf A. Widder.

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Widder, R.A., Dinslage, S., Rosentreter, A. et al. A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration. Graefes Arch Clin Exp Ophthalmol 252, 1971–1975 (2014). https://doi.org/10.1007/s00417-014-2795-z

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  • DOI: https://doi.org/10.1007/s00417-014-2795-z

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