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Allelic frequency database of 15 polymorphic autosomal STRs in the Malayalam-speaking population of Kerala, India

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Abstract

In this study, we assessed and established an allelic frequency database of Malayalam-speaking population of south western Indian state Kerala, using 15 polymorphic short tandem repeats (STRs) genetic markers. For this study, 464 unrelated healthy individuals were randomly selected following the ethical standards. The most polymorphic and most discriminating locus was D2S1338, with a value of 0.860 and 0.968, respectively. The range of heterozygosity extended from a minimum of 0.668 (TH01) to a maximum of 0.847 (D2S1338). The combined discrimination power (CPD) and combined exclusion power (CPE) were 1 and 0.999997861, respectively, for all 15 autosomal STR loci under study. The combined probability of match (CPM) and combined paternity index (CPI) for all 15 autosomal STR loci were found to be 9.85 × 10−19 and 4.18 × 105, respectively.

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Author notes

  1. R. Sreekumar, Ajeesh Thekkatavan, Pankaj Shrivastava and R. K. Kumawat contributed equally to this work.

Authors and Affiliations

  1. State Forensic Science Laboratory, Thiruvananthapuram, Kerala, 695010, India

    R. Sreekumar

  2. Biology Division, Regional Forensic Science Laboratory, Kannur, Kerala, 670002, India

    Ajeesh Thekkatavan

  3. DNA Fingerprinting Unit, State Forensic Science Laboratory, Department of Home (Police), Government of MP, Sagar, 470001, India

    Pankaj Shrivastava & Shivani Dixit

  4. DNA Division, State Forensic Science Laboratory, Jaipur, Rajasthan, 302016, India

    R. K. Kumawat

  5. Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, UP, India

    Gyaneshwer Chaubey

Authors
  1. R. Sreekumar
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  2. Ajeesh Thekkatavan
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  3. Pankaj Shrivastava
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  4. R. K. Kumawat
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  5. Shivani Dixit
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  6. Gyaneshwer Chaubey
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Corresponding author

Correspondence to Pankaj Shrivastava.

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Ethical approval

The study was approved by the ethical committee of Banaras Hindu University, Varanasi, India (Ref. No. I.Sc./ECM-XII/2018-19/06).

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Sreekumar, R., Thekkatavan, A., Shrivastava, P. et al. Allelic frequency database of 15 polymorphic autosomal STRs in the Malayalam-speaking population of Kerala, India. Int J Legal Med 134, 1679–1681 (2020). https://doi.org/10.1007/s00414-020-02286-0

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  • DOI: https://doi.org/10.1007/s00414-020-02286-0

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