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Impact of Cough and Unmet Needs in Chronic Cough: A Survey of Patients in Korea

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Abstract

Purpose

Chronic cough is a common problem in various populations. The present study assessed the impact of cough and unmet needs in Korean patients with chronic cough.

Methods

This cross-sectional multi-center study enrolled adult patients newly referred to clinic for assessment of chronic cough. A second group of patients with unexplained chronic cough following detailed assessment were recruited for comparison. Patients completed self-reported questionnaires, including cough characteristics, impact of cough on daily life, and unmet needs.

Results

A total of 447 subjects were recruited from six referral clinics, including 408 with chronic cough and 39 with unexplained chronic cough. Almost all patients reported that cough impacted their daily lives. Psychosocial impacts were more evident in unexplained cough patients compared to newly referred patients. Approximately 75% of newly referred patients had previously sought medical care for cough on multiple occasions, but the effectiveness of treatment was limited (70.3%) or absent (17.3%). The most frequent unmet need was the ineffectiveness of treatment (49.3%), followed by unclear diagnosis (30.1%). The majority of participants ( > 80%) expressed the need for further information on accessing cough specialists and disease management. The main problem faced by unexplained cough patients was poor cough control despite treatment (64%).

Conclusions

Chronic cough has a substantial impact on daily life and is worst in those whose cough remains unexplained following assessment. Ineffectiveness of treatment and unclear diagnosis were major unmet needs. Medical information about chronic cough was also lacking. Improvements in the management of chronic cough patients in Korea are necessary.

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References

  1. Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S et al (2015) The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J 45:1479–1481

    Article  Google Scholar 

  2. Morice AH, Millqvist E, Belvisi MG, Bieksiene K, Birring SS, Chung KF et al (2014) Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J 44:1132–1148

    Article  Google Scholar 

  3. Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J et al (2004) The diagnosis and management of chronic cough. Eur Respir J 24:481–492

    Article  CAS  Google Scholar 

  4. Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE et al (2006) Diagnosis and management of cough executive summary: accp evidence-based clinical practice guidelines. Chest 129:1S–23S

    Article  Google Scholar 

  5. Mcgarvey L (2013) The difficult-to-treat, therapy-resistant cough: why are current cough treatments not working and what can we do? Pulm Pharmacol Ther 26:528–531

    Article  CAS  Google Scholar 

  6. Birring SS, Prudon B, Carr AJ, Singh SJ, Morgan MD, Pavord ID (2003) Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ). Thorax 58:339–343

    Article  CAS  Google Scholar 

  7. French CL, Irwin RS, Curley FJ, Krikorian CJ (1998) Impact of chronic cough on quality of life. Arch Intern Med 158:1657–1661

    Article  CAS  Google Scholar 

  8. Song WJ, Morice AH, Kim MH, Lee SE, Jo EJ, Lee SM et al (2013) Cough in the elderly population: relationships with multiple comorbidity. PLoS ONE 8:E78081

    Article  CAS  Google Scholar 

  9. Chamberlain SA, Garrod R, Douiri A, Masefield S, Powell P, Bucher C et al (2015) The impact of chronic cough: a cross-sectional European Survey. Lung 193:401–408

    Article  Google Scholar 

  10. Song DJ, Song WJ, Kwon JW, Kim GW, Kim MA, Kim MY et al (2018) KAAACI evidence-based clinical practice guidelines for chronic cough in adults and children in Korea. Allergy Asthma Immunol Res 10:591–613

    Article  Google Scholar 

  11. Song W-J, Lee S-H, Kang M-G, Kim J-Y, Kim M-Y, Jo E-J et al (2015) Validation of the korean version of the European Community Respiratory Health Survey Screening Questionnaire for use in epidemiologic studies for adult asthma. Asia Pac Allergy 5:25–31

    Article  Google Scholar 

  12. Morice AH (2015) Over-the-counter cough medicines: new approaches. Pulm Pharmacol Ther 35:149–151

    Article  CAS  Google Scholar 

  13. Morice AH, Menon MS, Mulrennan SA, Everett CF, Wright C, Jackson J et al (2007) Opiate therapy in chronic cough. Am J Respir Crit Care Med 175:312–315

    Article  CAS  Google Scholar 

  14. Ryan NM, Birring SS, Gibson PG (2012) Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. Lancet 380:1583–1589

    Article  CAS  Google Scholar 

  15. Faruqi S, Murdoch RD, Allum F, Morice AH (2014) On the definition of chronic cough and current treatment pathways: an International Qualitative Study. Cough 10:5

    Article  Google Scholar 

  16. Chung KF, Mcgarvey L, Mazzone SB (2013) Chronic cough as a neuropathic disorder. Lancet Respir Med 1:414–422

    Article  Google Scholar 

  17. Song WJ, Morice AH (2017) Cough hypersensitivity syndrome: a few more steps forward. Allergy Asthma Immunol Res 9:394–402

    Article  CAS  Google Scholar 

  18. Polley L, Yaman N, Heaney L, Cardwell C, Murtagh E, Ramsey J et al (2008) Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires. Chest 134:295–302

    Article  Google Scholar 

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Correspondence to Woo-Jung Song.

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Kang, SY., Won, HK., Lee, S.M. et al. Impact of Cough and Unmet Needs in Chronic Cough: A Survey of Patients in Korea. Lung 197, 635–639 (2019). https://doi.org/10.1007/s00408-019-00258-9

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  • DOI: https://doi.org/10.1007/s00408-019-00258-9

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