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Comparison of endoscopic over-underlay technique with and without packing for repairing chronic perforation

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objective

This study was performed to compare the efficacy of the endoscopic modified cartilage over-underlay technique with and without packing for repairing chronic tympanic membrane (TM) perforations.

Methods

A total of 70 cases of chronic TM perforation were randomly allocated to endoscopic modified cartilage over-underlay myringoplasty groups with (n = 35) and without (n = 35) packing. The graft success rate and hearing outcomes were compared between the two groups. In addition, neovascularization scores were subjectively obtained.

Results

At 12 months postoperatively, the difference in graft success rate between the packing and no-packing groups was not significant (94.3% vs. 100.0%, P = 0.473). In addition, there were no significant differences between the two groups in the pre- or postoperative air–bone gap (ABG) (15.18 ± 2.73 vs. 15.07 ± 4.02, P = 0.623 and 8.63 ± 3.03 vs. 8.52 ± 4.50, P = 0.591) or mean ABG gain (6.56 ± 3.23 vs. 6.54 ± 2.83, P = 0.751). However, the average operating times were 43.6 ± 7.1 and 32.7 ± 2.1 min in the packing and no-packing groups, respectively (P < 0.001).

Conclusions

Surgical and hearing outcomes were comparable between patients with chronic TM perforation treated using the endoscopic modified over-underlay technique with and without packing. However, without packing, the procedure was less invasive and had a shorter operating time.

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Acknowledgements

The English in this document has been checked by at least two professional editors, both native speakers of English. For a certificate, please see: http://www.textcheck.com/certificate/m9hjvE

Funding

This study was supported by Health Commission of Zhejiang province, China (Grant#2021KY1186) and the Science and Technology Agency of Yiwu city, China (Grant#2018–3-76).

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Author notes

  1. Zhengcai Lou and Zihan Loue have contributed equally to this work.

Authors and Affiliations

  1. Department of Otorhinolaryngology, Yiwu Central Hospital, 699 Jiangdong Road, Yiwu City, Zhejiang Province, 322000, China

    Zhengcai Lou & Tian Lv

  2. Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, 200233, China

    Zihan Lou, Dongzhen Yu, Jingjing Wang & Zhengnong Chen

  3. Department of Otolaryngology Head and Neck Surgery and Center of Sleep Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Yishan Road 600, Shanghai, 200233, China

    Zihan Lou, Dongzhen Yu, Jingjing Wang & Zhengnong Chen

  4. Otolaryngological Institute of Shanghai Jiao Tong University, Yishan Road 600, Shanghai, 200233, China

    Zihan Lou, Dongzhen Yu, Jingjing Wang & Zhengnong Chen

  5. Shanghai Key Lab Sleep Disordered Breathing, Yishan Road 600, Shanghai, 200233, China

    Zihan Lou, Dongzhen Yu, Jingjing Wang & Zhengnong Chen

Authors
  1. Zhengcai Lou
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  2. Zihan Lou
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  4. Jingjing Wang
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  5. Tian Lv
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Contributions

ZL: interpretation of data for the work, design of the work, analysis of data for the work, drafting the work, and agreement to be accountable for all aspects of the work; final approval of the version to be published; ZL: interpretation of data for the work, analysis of data for the work, drafting the work and technical the diagram, agreement to be accountable for all aspects of the work, and final approval of the version to be published; DY and JW: analysis of data for the work, and final approval of the version to be published; TL: analysis of data for the work; agreement to be accountable for all aspects of the work; ZC: interpretation of data for the work, design of the work, and final approval of the version to be published.

Corresponding authors

Correspondence to Zhengcai Lou or Zhengnong Chen.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of the local Ethics Committee of YiWu central hospital review board and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all of the participants.

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Cite this article

Lou, Z., Lou, Z., Yu, D. et al. Comparison of endoscopic over-underlay technique with and without packing for repairing chronic perforation. Eur Arch Otorhinolaryngol 279, 4761–4768 (2022). https://doi.org/10.1007/s00405-022-07254-5

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  • DOI: https://doi.org/10.1007/s00405-022-07254-5

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