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The bacteriology of recurrent acute exacerbations of chronic rhinosinusitis: a longitudinal analysis

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study was to describe the microbiology of recurrent acute exacerbations of chronic rhinosinusitis over time.

Methods

Retrospective review of patients with recurrent acute exacerbations of chronic rhinosinusitis who underwent endoscopic-guided cultures during acute exacerbations of chronic rhinosinusitis.

Results

386 cultures were obtained from 112 patients during recurrent acute exacerbations of CRS. A change of bacterial isolates during the course of recurrent exacerbations was observed in 68% (76/112) of patients, necessitating a change of treatment in 40% (45/112). The main risk factor for the subsequent change in cultures was polymicrobial growth. Sinus surgery was not associated with subsequent change in cultured isolates. Resistant strains developed in 11.6% (13/112) of patients, of whom those with abnormal mucociliary clearance being at the highest risk.

Conclusion

Repeated middle meatal cultures should be considered in patients with recurrent exacerbations of CRS, particularly in cases not responding to standard therapy.

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Data availability

Data available.

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Funding

No funding was received for this research.

Author information

Authors and Affiliations

  1. Department of Otorhinolaryngology Head and Neck Surgery, Rabin Medical Center, Petah Tiqva, Israel

    Dan Yaniv, Igor Vainer & Ethan Soudry

  2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

    Dan Yaniv, Daniel Stern, Igor Vainer, Dafna Yahav & Ethan Soudry

  3. Department of Otorhinolaryngology, Head and Neck Surgery, Edith Wolfson Medical Center, Holon, Israel

    Daniel Stern

  4. Microbiologic Laboratory, Rabin Medical Center, Petah Tiqva, Israel

    Haim Ben Zvi

  5. Infectious Diseases Unit, Rabin Medical Center, Petah Tiqva, Israel

    Dafna Yahav

Authors
  1. Dan Yaniv
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  2. Daniel Stern
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  3. Igor Vainer
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  4. Haim Ben Zvi
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  5. Dafna Yahav
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  6. Ethan Soudry
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Corresponding author

Correspondence to Dan Yaniv.

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Yaniv, D., Stern, D., Vainer, I. et al. The bacteriology of recurrent acute exacerbations of chronic rhinosinusitis: a longitudinal analysis. Eur Arch Otorhinolaryngol 277, 3051–3057 (2020). https://doi.org/10.1007/s00405-020-06157-7

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  • DOI: https://doi.org/10.1007/s00405-020-06157-7

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