Skip to main content
SpringerLink
Log in

Change in Warthin’s tumor incidence: a 20-year joinpoint trend analysis

  • Head and Neck
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

The incidence of Warthin’s tumor (WT) has increased worldwide. In this study, we aimed to evaluate the incidence of WT in our hospital, which provides health care for an extremely large population.

Methods

We retrospectively evaluated 573 patients, comprising 345 males and 228 females, who all experienced parotid tumor for the past 20 years. Patients with WT that were operated in the last 20 years were evaluated according to the number of patients per year to determine the annual WT increase trend.

Results

In the distribution of WT over the years of surgery, the ratio of WT to all tumors irregularly changed. Furthermore, the total number of parotidectomies per year increased in time. We investigated whether WT had any increasing trend over the years. The annual percentage change (APC) of WT was calculated, and according to the segmented regression analysis, the APC was insignificant (APC = 4.3, 95% CI = − 3.6–12.9, P = 0.300).

Conclusion

The incidence of WT has increased across the world. However, in our study, no significant APC was observed according to the segmented regression analysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Orabona GD, Abbate V, Piombino P et al (2015) Warthin’s tumour: aetiopathogenesis dilemma, ten years of our experience. J Craniomaxillofac Surg 43:427–431

    Article  PubMed  Google Scholar 

  2. Mantsopoulos K, Goncalves M, Koch M et al (2018) Extracapsular dissection for warthin tumors despite risk of ipsilateral metachronous occurrence. Laryngoscope 128:2521–2524

    Article  PubMed  Google Scholar 

  3. Teymoortash A (2013) Back to roots of Warthin’s tumor of the parotid gland. Eur Arch Otorhinolaryngol 270:2397–2402

    Article  PubMed  Google Scholar 

  4. Patel DK, Morton RP (2016) Demographics of benign parotid tumours: Warthin’s tumour versus other benign salivary tumours. Acta Otolaryngol 136:83–86

    Article  PubMed  Google Scholar 

  5. Lee DH, Yoon TM, Lee JK et al (2019) Surgical treatment strategy in Warthin tumor of the parotid gland. Braz J Otorhinolaryngol 85:546–550

    Article  PubMed  Google Scholar 

  6. Kadletz L, Grasl S, Perisanidis C et al (2019) Rising incidences of Warthin’s tumors may be linked to obesity: a single-institutional experience. Eur Arch Otorhinolaryngol 276:1191–1196

    Article  PubMed  Google Scholar 

  7. Psychogios G, Vlastos I, Thölken R et al (2020) Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany. Eur Arch Otorhinolaryngol. https://doi.org/10.1007/s00405-020-05894

    Article  PubMed  Google Scholar 

  8. Luers JC, Guntinas-Lichius O, Klussmann JP et al (2016) The incidence of Warthin tumours and pleomorphic adenomas in the parotid gland over a 25-year period. Clin Otolaryngol 41:793–797

    Article  CAS  PubMed  Google Scholar 

  9. Joinpoint Regression Program, Version 4.7.0.0—February 2019; statistical methodology and applications branch, surveillance research program, National Cancer Institute. Accessed 10 Mar 2020

  10. Jechova A, Kuchar M, Novak S et al (2019) The role of fine-needle aspiration biopsy (FNAB) in Warthin tumour diagnosis and management. Eur Arch Otorhinolaryngol 276:2941–2946

    Article  PubMed  Google Scholar 

  11. Köybaşioğlu FF, Önal BB, Han Ü et al (2020) Cytomorphological findings in diagnosis of Warthin tumor. Turk J Med Sci 50:148–154

    PubMed  PubMed Central  Google Scholar 

  12. Shetty A, Geethamani V (2016) Role of fine-needle aspiration cytology in the diagnosis of major salivary gland tumors: a study with histological and clinical correlation. J Oral Maxillofac Pathol 20:224–229

    Article  PubMed  PubMed Central  Google Scholar 

  13. Franzen AM, Kaup Franzen C, Guenzel T et al (2018) Increased incidence of Warthin tumours of the parotid gland: a 42-year evaluation. Eur Arch Otorhinolaryngol 275:2593–2598

    Article  PubMed  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Department of Otorhinolaryngology, Gaziantep University, Gaziantep, Turkey

    Orhan Tunç, Burhanettin Gönüldaş, Yusuf Arslanhan & Muzaffer Kanlıkama

Authors
  1. Orhan Tunç
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Burhanettin Gönüldaş
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yusuf Arslanhan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Muzaffer Kanlıkama
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Orhan Tunç.

Ethics declarations

Conflict of interest

The authors declared no conflict of interest.

Ethical approval

The study was carried out after receiving the approval of the Gaziantep University Clinical Research Ethics Committee (Gaziantep University Clinical Research Ethics Committee, Permit Number; 2020/134).

Informed consent

Informed consent form was obtained from all patients included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tunç, O., Gönüldaş, B., Arslanhan, Y. et al. Change in Warthin’s tumor incidence: a 20-year joinpoint trend analysis. Eur Arch Otorhinolaryngol 277, 3431–3434 (2020). https://doi.org/10.1007/s00405-020-06081-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-020-06081-w

Keywords

Search

Navigation