Skip to main content
Log in

Indications and results of extended total laryngectomy with en-bloc resection of overlying cervical skin

  • Head and Neck
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

Extended total laryngectomy with en-bloc resection of overlying cervical skin (ETL) is indicated in cases with infiltration of the pre-laryngeal soft tissues. The present study analyses the surgical indications and the results of ETL in our hospital.

Methods

Retrospective review of 38 patients treated with an ETL during the period 1988–2016.

Results

The indications for ETL were the initial treatment of tumors with extralaryngeal extension (n = 16), salvage treatment after failure of partial surgery or radiotherapy (n = 17), and total laryngectomy in patients with infection or fibrosis of the skin over the larynx (n = 5). The surgical defect was reconstructed with local flaps in 3 cases, with pectoralis major flaps in 34 cases, and with an internal mammary artery perforator flap in one case. The rate of pharyngocutaneous fistula in the postoperative period was 16%. 5-year cancer-specific survival for patients treated with an ETL was 67.1%. The patients with positive margins and those operated as a salvage treatment after failure of previous treatments showed worse survival.

Conclusions

ETL offers acceptable oncological results for patients with tumors with extralaryngeal extension. Myocutaneous or myofascial pectoralis major flaps allow for adequate reconstruction of the surgical defect with a low rate of complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. García Lorenzo J, Montoro Martínez V, Rigo Quera A, Codina Aroca A, López Vilas M, Quer Agustí M, León Vintró X (2017) Modifications in the treatment of advanced laryngeal cancer throughout the last 30 years. Eur Arch Otorhinolaryngol 274:3449–3455

    Article  Google Scholar 

  2. Olsen KD (2010) Reexamining the treatment of advanced laryngeal cancer. Head Neck 32:1–7

    PubMed  Google Scholar 

  3. Ampil FL, Nathan CO, Caldito G, Lian TF, Aarstad RF, Krishnamsetty RM (2004) Total laryngectomy and postoperative radiotherapy for T4 laryngeal cancer: a 14-year review. Am J Otolaryngol 25:88–93

    Article  Google Scholar 

  4. Agra IM, Ferlito A, Takes RP, Silver CE, Olsen KD, Stoeckli SJ et al (2012) Diagnosis and treatment of recurrent laryngeal cancer following initial nonsurgical therapy. Head Neck 34:727–735

    Article  Google Scholar 

  5. Guerrier Y (1987) Les laryngectomies totales élargies. In: Traité de technique chirurgicale O.R.L. et cervico-faciale, vol 3. Masson, Paris, pp 331–339

  6. Croce A, Moretti A, Bianchedi M, Neri G, Falcone G (1995) Widened forwarding total laryngectomy ("squared laryngectomy"). Hints of surgical techniques and personal experience. Acta Otorhinolaryngol Ital 15:355–360

    CAS  PubMed  Google Scholar 

  7. León X, Orús C, Quer M (2002) Design, maintenance, and exploitation of an oncologic database for patients with malignant tumors of the head and neck. Acta Otorrinolaringol Esp 53:185–190

    Article  Google Scholar 

  8. Lam KH (1983) Extralaryngeal spread of cancer of the larynx: a study with whole-organ sections. Head Neck Surg 5:410–424

    Article  CAS  Google Scholar 

  9. Beitler JJ, Muller S, Grist WJ, Corey A, Klein AM, Johns MM et al (2010) Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. J Clin Oncol 28:2318–2322

    Article  Google Scholar 

  10. Chen SA, Muller S, Chen AY, Hudgins PA, Shin DM, Khuri F, Saba NF, Beitler JJ (2011) Patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. Cancer 117:5047–5051

    Article  Google Scholar 

  11. Gallo A, Moi R, Simonelli M, Vitolo D, Fiorella ML, Marvaso V, Manciocco V, de Vincentiis M (2001) Salvage resection after previous laryngeal surgery: total laryngectomy with en bloc resection of the overlying cervical skin. Arch Otolaryngol Head Neck Surg 127:786–789

    CAS  PubMed  Google Scholar 

  12. Mosleh M, Fathy H (2014) Advanced laryngeal cancer with skin infiltration: survival analysis. Egypt J Otolaryngol 30:122–125

    Article  Google Scholar 

  13. Zahran M, Youssef A (2018) The role of regional flaps in locally advanced cancer larynx with skin invasion Egypt. J Otolaryngol 34:289–292

    Google Scholar 

  14. Emerick KS, Herr MA, Deschler DG (2014) Supraclavicular flap reconstruction following total laryngectomy. Laryngoscope 124:1777–1782

    Article  Google Scholar 

  15. Schellekens PP, Paes EC, Hage JJ, van der Wal MB, Bleys RL, Kon M (2011) Anatomy of the vascular pedicle of the internal mammary artery perforator (IMAP) flap as applied for head and neck reconstruction. J Plast Reconstr Aesthet Surg 64:53–57

    Article  Google Scholar 

  16. Chiesa Estomba CM, González García JA, Sistiaga Suarez JA, Thomas Arrizabalaga I, Larruscain Sarasola E, Altuna Mariezcurrena X (2018) Efficacy of the myofascial pectoralis major flap in the reduction of salivary fistulas after salvage total laryngectomy. Acta Otorrinolaringol Esp 69:99–104

    Article  Google Scholar 

  17. Casasayas M, Sansa A, García-Lorenzo J, López M, Orús C, Peláez X, Quer M, León X (2019) Pharyngocutaneous fistula after total laryngectomy: multivariate analysis of risk factors and a severity-based classification proposal. Eur Arch Otorhinolaryngol 276:143–151

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xavier León.

Ethics declarations

Conflict of interest

The authors declare no conflict of interest.

Research involving human participants

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional, regional and national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed consent

For this type of study, formal consent is not required.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 13 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

León, X., López, M., García, J. et al. Indications and results of extended total laryngectomy with en-bloc resection of overlying cervical skin. Eur Arch Otorhinolaryngol 276, 3179–3184 (2019). https://doi.org/10.1007/s00405-019-05573-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-019-05573-8

Keywords

Navigation