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Long-term quality of life and its predictive factors after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer

  • Head and Neck
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Abstract

The aims of this study were to evaluate long-term quality of life (QoL) and to determine its predictive factors after oncologic surgery and free flap reconstruction in patients with oral or oropharyngeal cancer. Patients treated at our institution between 2000 and 2009, who are alive and disease-free at least 1 year after therapy, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific H&N35 module. Eighty patients were included in our study. Global QoL score was 69.3 ± 22.7 %. Global QoL and general symptoms were correlated with T stage, whereas head and neck symptoms were correlated with T stage and tumor involvement of the tongue base. Emotional and social functioning scales, and resumption of professional activity were significantly associated with global QoL. In conclusion, T stage, tumor involvement of the tongue base, professional status and emotional and social functions were the main determinants of QoL in our study.

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Authors and Affiliations

  1. Department of Surgery, Institut Universitaire de la Face et du Cou, 31 Avenue de Valombrose, 06103, Nice, France

    Cédric S. Pierre, Olivier Dassonville, Gilles Poissonnet, José Santini & Alexandre Bozec

  2. Department of Statistics, Centre Antoine Lacassagne, Nice, France

    Emmanuel Chamorey & Marc Ettaiche

  3. Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France

    Frédéric Peyrade

  4. Department of Radiotherapy, Centre Antoine Lacassagne, Nice, France

    Karen Benezery

  5. Department of Pathology, Centre Antoine Lacassagne, Nice, France

    Anne Sudaka

Authors
  1. Cédric S. Pierre
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  2. Olivier Dassonville
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  3. Emmanuel Chamorey
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  4. Gilles Poissonnet
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  5. Marc Ettaiche
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  6. José Santini
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  7. Frédéric Peyrade
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  8. Karen Benezery
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  9. Anne Sudaka
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  10. Alexandre Bozec
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Correspondence to Alexandre Bozec.

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Pierre, C.S., Dassonville, O., Chamorey, E. et al. Long-term quality of life and its predictive factors after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer. Eur Arch Otorhinolaryngol 271, 801–807 (2014). https://doi.org/10.1007/s00405-013-2592-z

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  • DOI: https://doi.org/10.1007/s00405-013-2592-z

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