Abstract
Purpose
To determine whether preoperative vaginal cleansing with iodine-based solution prior to hysteroscopy, reduces postoperative infection rate compared to no vaginal cleansing.
Methods
A retrospective study at a single tertiary, university affiliated hospital of all individuals who have had an office hysteroscopy. Study group consisted of patients who have had preoperative vaginal cleansing with iodine-based solution and were compared to those who have not. Any procedural related complaints at the 30 days following the hysteroscopy were recorded.
Results
A total of 505 were available for analysis, 183 in the study group and 322 in the control group. The most common indications for operation were infertility evaluation (33.9% vs. 28.6%) and retained products of conception (33.3% vs. 29.2%), and most common procedures were diagnostic only (49.7% vs. 42.5%) followed by adhesiolysis (12% vs. 14.3%).
No statistical differences were noted with regards to postoperative infections, as only one case of pelvic inflammatory disease was noted, in the iodine cleansing group (0.19% for postoperative infection).
Conclusion
Our comparative study may suggest that the use of preoperative iodine solution prior to office hysteroscopy does not decrease the postoperative infection rate up to 30 days, thus can be avoided.
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Data availability
The data that support the findings of this study are available from the corresponding author, upon reasonable request.
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Acknowledgements
We would like to thank Ms. Perach Chen Elkayam, from the Department of Community Medicine and Epidemiology, the Lady Davis Carmel Medical Center, for her aid in statistical computation and analysis.
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NC: Protocol development, data collection, manuscript writing. HK: Data collection, manuscript reviewing. LAF: Data collection, manuscript reviewing. MP: Manuscript reviewing. YK: Manuscript reviewing. OL: Manuscript reviewing. AZ: Protocol development, manuscript writing. All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by NC, HIK and LAF. The first draft of the manuscript was written by NC, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Cohen, N., Kedem, H.I., Abu-Foul, L. et al. Does vaginal cleansing with iodine decreases infection rate in office hysteroscopy?. Arch Gynecol Obstet 308, 1791–1796 (2023). https://doi.org/10.1007/s00404-023-07199-y
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DOI: https://doi.org/10.1007/s00404-023-07199-y