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Estimated intake and major food sources of flavonoids among US adults: changes between 1999–2002 and 2007–2010 in NHANES

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Abstract

Purpose

This study was conducted to: (1) demonstrate an updated method for estimating flavonoid intake of US adults by combining USDA flavonoid databases and NHANES food consumption data; (2) document the intake and major food sources of flavonoids among US adults; and (3) determine whether the intake and major sources of dietary flavonoids have changed during the past decade in the USA.

Methods

A cross-sectional population-based study. Differences over time in the average daily intake and food sources of flavonoids were estimated using food consumption data from NHANES 1999–2002 (n = 8833) and 2007–2010 (n = 9801).

Results

The total flavonoid intake of US adults aged 19 years and older remained unchanged between 1999–2002 (201.9 mg/d) and 2007–2010 (200.1 mg/d), with tea being the top food source of flavonoids. However, intake of anthocyanidins increased during this period, mainly due to greater consumption of berries and wine, which was consistent with the increase in per capita consumption of these foods based on USDA food availability data.

Conclusions

The results of this study provide updated information on flavonoid intake and food contributors and warrant further studies on the health implications of flavonoid intake.

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References

  1. Arts IC (2008) A review of the epidemiological evidence on tea, flavonoids, and lung cancer. J Nutr 138(8):1561S–1566S

    CAS  Google Scholar 

  2. Geybels MS, Verhage BA, Arts IC, van Schooten FJ, Goldbohm RA, van den Brandt PA (2013) Dietary flavonoid intake, black tea consumption, and risk of overall and advanced stage prostate cancer. Am J Epidemiol 177(12):1388–1398

    Article  Google Scholar 

  3. Zamora-Ros R, Sacerdote C, Ricceri F, Weiderpass E, Roswall N, Buckland G, St-Jules DE, Overvad K, Kyro C, Fagherazzi G, Kvaskoff M, Severi G, Chang-Claude J, Kaaks R, Nothlings U, Trichopoulou A, Naska A, Trichopoulos D, Palli D, Grioni S, Mattiello A, Tumino R, Gram IT, Engeset D, Huerta JM, Molina-Montes E, Arguelles M, Amiano P, Ardanaz E, Ericson U, Lindkvist B, Nilsson LM, Kiemeney LA, Ros M, Bueno-de-Mesquita HB, Peeters PH, Khaw KT, Wareham NJ, Knaze V, Romieu I, Scalbert A, Brennan P, Wark P, Vineis P, Riboli E, Gonzalez CA (2014) Flavonoid and lignan intake in relation to bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Br J Cancer 111:1870–1880

    Article  CAS  Google Scholar 

  4. Arab L, Khan F, Lam H (2013) Tea consumption and cardiovascular disease risk. Am J Clin Nutr 98(6 Suppl):1651S–1659S. doi:10.3945/ajcn.113.059345

    Article  CAS  Google Scholar 

  5. Wang X, Ouyang YY, Liu J, Zhao G (2014) Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies. Br J Nutr 111(1):1–11

    Article  CAS  Google Scholar 

  6. Zujko ME, Witkowska AM, Waskiewicz A, Sygnowska E (2012) Estimation of dietary intake and patterns of polyphenol consumption in Polish adult population. Adv Med Sci 57(2):375–384

    Article  CAS  Google Scholar 

  7. Hernandez-Elizondo J, Monteagudo C, Murcia MA, Olea N, Olea-Serrano F, Mariscal-Arcas M (2013) Assessment of the estrogenicity of the diet of a healthy female Spanish population based on its isoflavone content. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30(4):627–633

    Article  CAS  Google Scholar 

  8. Zhang Y, Li Y, Cao C, Cao J, Chen W, Zhang Y, Wang C, Wang J, Zhang X, Zhao X (2010) Dietary flavonol and flavone intakes and their major food sources in Chinese adults. Nutr Cancer 62(8):1120–1127

    Article  CAS  Google Scholar 

  9. Drossard C, Bolzenius K, Kunz C, Kersting M (2013) Anthocyanins in the diet of children and adolescents: intake, sources and trends. Eur J Nutr 52(2):667–676

    Article  CAS  Google Scholar 

  10. Chun OK, Kim D-O, Smith N, Shroeder D, Han JT (2005) Daily consumption of phenolics and total antioxidant capacity from fruit and vegetables in the American diet. J Sci Food Agric 85:1715–1724

    Article  CAS  Google Scholar 

  11. Chun OK, Lee SG, Wang Y, Vance T, Song WO (2012) Estimated flavonoid intake of the elderly in the United States and around the world. J Nutr Gerontol Geriatr 31(3):190–205

    Article  Google Scholar 

  12. Hertog MG, Hollman PC, Katan MB, Kromhout D (1993) Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr Cancer 20(1):21–29

    Article  CAS  Google Scholar 

  13. Knekt P, Jarvinen R, Reunanen A, Maatela J (1996) Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ 312(7029):478–481

    Article  CAS  Google Scholar 

  14. Murphy MM, Barraj LM, Herman D, Bi X, Cheatham R, Randolph RK (2012) Phytonutrient intake by adults in the United States in relation to fruit and vegetable consumption. J Acad Nutr Diet 112(2):222–229

    Article  CAS  Google Scholar 

  15. Chun OK, Floegel A, Chung SJ, Chung CE, Song WO, Koo SI (2010) Estimation of antioxidant intakes from diet and supplements in US adults. J Nutr 140(2):317–324

    Article  CAS  Google Scholar 

  16. Chun OK, Chung SJ, Song WO (2007) Estimated dietary flavonoid intake and major food sources of US adults. J Nutr 137(5):1244–1252

    CAS  Google Scholar 

  17. Agricultural Research Service (2013) USDA database for the flavonoid content of selected foods, release 3.1, US Department of Agriculture

  18. Agricultural Research Service (2008) USDA database for the isoflavone content of selected foods, release 2.0, US Department of Agriculture

  19. Agricultural Research Service (1999) USDA database for the isoflavone content of selected foods, release 1.0. US Department of Agriculture

  20. Agricultural Research Service (2003) USDA database for the flavonoid content of selected foods, release 1, US Department of Agriculture

  21. Agricultural Research Service (2006) USDA database for the flavonoid content of selected foods, release 2, US Department of Agriculture

  22. Agricultural Research Service (2007) USDA database for the flavonoid content of selected foods, release 2.1, US Department of Agriculture

  23. Agricultural Research Service (2011) USDA database for the flavonoid content of selected foods, release 3, US Department of Agriculture

  24. Maras JE, Talegawkar SA, Qiao N, Lyle B, Ferrucci L, Tucker KL (2011) Flavonoid intakes in the Baltimore Longitudinal Study of Aging. J Food Compost Anal 24(8):1103–1109

    Article  CAS  Google Scholar 

  25. Beking K, Vieira A (2011) An assessment of dietary flavonoid intake in the UK and Ireland. Int J Food Sci Nutr 62(1):17–19

    Article  CAS  Google Scholar 

  26. Mullie P, Clarys P, Deriemaeker P, Hebbelinck M (2008) Estimation of daily human intake of food flavonoids. Int J Food Sci Nutr 59(4):291–298

    Article  CAS  Google Scholar 

  27. Zamora-Ros R, Knaze V, Lujan-Barroso L, Slimani N, Romieu I, Fedirko V, de Magistris MS, Ericson U, Amiano P, Trichopoulou A, Dilis V, Naska A, Engeset D, Skeie G, Cassidy A, Overvad K, Peeters PH, Huerta JM, Sanchez MJ, Quiros JR, Sacerdote C, Grioni S, Tumino R, Johansson G, Johansson I, Drake I, Crowe FL, Barricarte A, Kaaks R, Teucher B, Bueno-de-Mesquita HB, van Rossum CT, Norat T, Romaguera D, Vergnaud AC, Tjonneland A, Halkjaer J, Clavel-Chapelon F, Boutron-Ruault MC, Touillaud M, Salvini S, Khaw KT, Wareham N, Boeing H, Forster J, Riboli E, Gonzalez CA (2011) Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort. Br J Nutr 106(12):1915–1925

    Article  CAS  Google Scholar 

  28. McCullough ML, Peterson JJ, Patel R, Jacques PF, Shah R, Dwyer JT (2012) Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults. Am J Clin Nutr 95(2):454–464

    Article  CAS  Google Scholar 

  29. Wang Y, Gapstur SM, Gaudet MM, Peterson JJ, Dwyer JT, McCullough ML (2014) Evidence for an association of dietary flavonoid intake with breast cancer risk by estrogen receptor status is limited. J Nutr 144(10):1603–1611

    Article  CAS  Google Scholar 

  30. Johannot L, Somerset SM (2006) Age-related variations in flavonoid intake and sources in the Australian population. Public Health Nutr 9(8):1045–1054

    Article  Google Scholar 

  31. Kapiszewska M, Miskiewicz M, Ellison PT, Thune I, Jasienska G (2006) High tea consumption diminishes salivary 17beta-estradiol concentration in Polish women. Br J Nutr 95(5):989–995

    Article  CAS  Google Scholar 

  32. Chun OK, Chung SJ, Song WO (2009) Urinary isoflavones and their metabolites validate the dietary isoflavone intakes in US adults. J Am Diet Assoc 109(2):245–254

    Article  CAS  Google Scholar 

  33. Ahuja JKC, Montville JB, Omolewa-Tomobi G, Heendeniya KY, Martin CL, Steinfeldt LC, Anand J, Adler ME, LaComb RP, Moshfegh AJ (2012) USDA food and nutrient database for dietary studies, 5.0, US Department of Agriculture, Agricultural Research Service, Beltsville

  34. Siriwoharn T, Wrolstad RE, Finn CE, Pereira CB (2004) Influence of cultivar, maturity, and sampling on blackberry (Rubus L. Hybrids) anthocyanins, polyphenolics, and antioxidant properties. J Agric Food Chem 52(26):8021–8030

    Article  CAS  Google Scholar 

  35. Romero C, Brenes M, Yousfi K, Garcia P, Garcia A, Garrido A (2004) Effect of cultivar and processing method on the contents of polyphenols in table olives. J Agric Food Chem 52(3):479–484

    Article  CAS  Google Scholar 

  36. Wolfe KL, Liu RH (2003) Apple peels as a value-added food ingredient. J Agric Food Chem 51(6):1676–1683

    Article  CAS  Google Scholar 

  37. Klopotek Y, Otto K, Bohm V (2005) Processing strawberries to different products alters contents of vitamin C, total phenolics, total anthocyanins, and antioxidant capacity. J Agric Food Chem 53(14):5640–5646

    Article  CAS  Google Scholar 

  38. Adom KK, Sorrells ME, Liu RH (2005) Phytochemicals and antioxidant activity of milled fractions of different wheat varieties. J Agric Food Chem 53(6):2297–2306

    Article  CAS  Google Scholar 

  39. Nicolas JJ, Richard-Forget FC, Goupy PM, Amiot MJ, Aubert SY (1994) Enzymatic browning reactions in apple and apple products. Crit Rev Food Sci Nutr 34(2):109–157

    Article  CAS  Google Scholar 

  40. Niseteo T, Komes D, Belscak-Cvitanovic A, Horzic D, Budec M (2012) Bioactive composition and antioxidant potential of different commonly consumed coffee brews affected by their preparation technique and milk addition. Food Chem 134:1870–1877

    Article  CAS  Google Scholar 

  41. National Center for Health Statistics (2002) National Health and Nutrition Examination Survey Questionnaire, 1999–2000 data files CDC, Hyattsville

  42. National Center for Health Statistics (2004) National Health and Nutrition Examination Survey Questionnaire, 2001–2002 data files CDC, Hyattsville

  43. National Center for Health Statistics (2010) National Health and Nutrition Examination Survey Questionnaire, 2007–2008 data files CDC, Hyattsville

  44. National Center for Health Statistics (2012) National Health and Nutrition Examination Survey Questionnaire, 2009–2010 data files CDC, Hyattsville

  45. Substance Abuse and Mental Health Services Administration (2014) Results from the 2013 national survey on drug use and health: summary of national findings. Substance Abuse and Mental Health Services Administration, Rockville

    Google Scholar 

  46. ERS Food Availability Data System (2014) http://www.ers.usda.gov/data-products/food-availability-(per-capita)-data-system/.aspx

  47. Economic Research Service (ERS) US Department of Agriculture (USDA) (2014) Food availability (per capita) data system

  48. Kirkpatrick S, Tarasuk V (2003) The relationship between low income and household food expenditure patterns in Canada. Public Health Nutr 6(6):589–597

    Article  Google Scholar 

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Acknowledgments

This research received no specific grant from any funding agency, commercial or not-for-profit sectors.

Conflict of interest

K. Kim, T. M. Vance, and O. K. Chun have no conflict of interest on the publication of this manuscript.

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Correspondence to Ock K. Chun.

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Kim, K., Vance, T.M. & Chun, O.K. Estimated intake and major food sources of flavonoids among US adults: changes between 1999–2002 and 2007–2010 in NHANES. Eur J Nutr 55, 833–843 (2016). https://doi.org/10.1007/s00394-015-0942-x

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  • DOI: https://doi.org/10.1007/s00394-015-0942-x

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