Abstract
Purpose
This study analyzes the implementation of the routine use of quadratus lumborum blocks (QLBs) on postoperative pain and opioid consumption among children undergoing laparoscopic appendectomy compared to those not receiving regional anesthesia.
Methods
Children undergoing laparoscopic appendectomy within a multi-hospital children’s healthcare system were retrospectively reviewed from 2017 to 2021. Patients were stratified by appendicitis type (uncomplicated vs. complicated). Pain scores and opioid consumption in the post-anesthesia care unit (PACU) and within the first 24 h postoperatively were compared by block status (no block [NB] vs. QLB) and appendicitis type.
Results
2033 patients were reviewed, and 610 received a QLB. The frequency of rescue opioid use was reduced in the PACU (uncomplicated: QLB 46.6% vs. NB 54.6%, p = 0.005; complicated: QLB 28.5% vs. NB 39.9%, p = 0.01) and postoperatively (complicated: QLB 33.7% vs. NB 52.9%, p < 0.001) for those who received a QLB. This resulted in reduced opioid consumption as measured by morphine milligram equivalents per kilogram postoperatively.
Conclusion
QLBs can be safely administered in children and provide improvements in opioid consumption postoperatively. QLBs should remain a strongly favored regional anesthetic technique because of their wide applicability for abdominal surgeries to minimize rescue opioid analgesic use.
Type of study
Retrospective comparative study.
Level of evidence
Level III.
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Data availability
The data that support the findings of this study are available on request from the corresponding author (DP).
Abbreviations
- ASA:
-
American Society of Anesthesiologists
- CA:
-
Complicated appendicitis
- EO:
-
External oblique
- ERAS:
-
Enhanced recovery after surgery
- HLOS:
-
Hospital length of stay
- IO:
-
Internal oblique
- IQR:
-
Interquartile range
- kg:
-
Kilograms
- LA:
-
Local anesthetic
- LOS:
-
Length of stay
- MME:
-
Morphine milligram equivalents
- NB:
-
No block
- NRS:
-
Numeric rating scale
- NSAIDs:
-
Non-steroidal anti-inflammatory drugs
- NSQIP:
-
National Surgical Quality Improvement Program
- OR:
-
Operating room
- PACU:
-
Post-anesthesia care unit
- QL:
-
Quadratus lumborum
- QLB:
-
Quadratus lumborum block
- TA:
-
Transversus abdominis
- TAP:
-
Transversus abdominis plane
- UA:
-
Uncomplicated appendicitis
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L.B., K.S., and R.L. contributed to the conception and design of the research project. K.S., D.P., K.F., and B.B. contributed through data acquisition. S.J.M. and D.P. contributed through data analysis. All authors contributed to the interpretation of the data and its analysis. D.P. and S.J.M. contributed to the drafting of the manuscript and development of all figures. All authors critically revised the manuscript, agreed to be fully accountable for ensuring the integrity and accuracy of the work, and read and approved the final manuscript.
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Pace, D., Mack, S.J., Sadacharam, K. et al. Implementation of a quadratus lumborum regional block protocol with assessment of effectiveness for patients with appendicitis: a quality improvement project. Pediatr Surg Int 39, 267 (2023). https://doi.org/10.1007/s00383-023-05522-x
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DOI: https://doi.org/10.1007/s00383-023-05522-x