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Implementation of a quadratus lumborum regional block protocol with assessment of effectiveness for patients with appendicitis: a quality improvement project

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Abstract

Purpose

This study analyzes the implementation of the routine use of quadratus lumborum blocks (QLBs) on postoperative pain and opioid consumption among children undergoing laparoscopic appendectomy compared to those not receiving regional anesthesia.

Methods

Children undergoing laparoscopic appendectomy within a multi-hospital children’s healthcare system were retrospectively reviewed from 2017 to 2021. Patients were stratified by appendicitis type (uncomplicated vs. complicated). Pain scores and opioid consumption in the post-anesthesia care unit (PACU) and within the first 24 h postoperatively were compared by block status (no block [NB] vs. QLB) and appendicitis type.

Results

2033 patients were reviewed, and 610 received a QLB. The frequency of rescue opioid use was reduced in the PACU (uncomplicated: QLB 46.6% vs. NB 54.6%, p = 0.005; complicated: QLB 28.5% vs. NB 39.9%, p = 0.01) and postoperatively (complicated: QLB 33.7% vs. NB 52.9%, p < 0.001) for those who received a QLB. This resulted in reduced opioid consumption as measured by morphine milligram equivalents per kilogram postoperatively.

Conclusion

QLBs can be safely administered in children and provide improvements in opioid consumption postoperatively. QLBs should remain a strongly favored regional anesthetic technique because of their wide applicability for abdominal surgeries to minimize rescue opioid analgesic use.

Type of study

Retrospective comparative study.

Level of evidence

Level III.

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Data availability

The data that support the findings of this study are available on request from the corresponding author (DP).

Abbreviations

ASA:

American Society of Anesthesiologists

CA:

Complicated appendicitis

EO:

External oblique

ERAS:

Enhanced recovery after surgery

HLOS:

Hospital length of stay

IO:

Internal oblique

IQR:

Interquartile range

kg:

Kilograms

LA:

Local anesthetic

LOS:

Length of stay

MME:

Morphine milligram equivalents

NB:

No block

NRS:

Numeric rating scale

NSAIDs:

Non-steroidal anti-inflammatory drugs

NSQIP:

National Surgical Quality Improvement Program

OR:

Operating room

PACU:

Post-anesthesia care unit

QL:

Quadratus lumborum

QLB:

Quadratus lumborum block

TA:

Transversus abdominis

TAP:

Transversus abdominis plane

UA:

Uncomplicated appendicitis

References

  1. Harbaugh CM, Lee JS, Hu HM et al (2018) Persistent opioid use among pediatric patients after surgery. Pediatrics 141:e20172439. https://doi.org/10.1542/peds.2017-2439

    Article  PubMed  Google Scholar 

  2. Yaster M, McNaull PP, Davis PJ (2020) The opioid epidemic in pediatrics: a 2020 update. Curr Opin Anaesthesiol 33:327–334. https://doi.org/10.1097/ACO.0000000000000865

    Article  PubMed  Google Scholar 

  3. Rafeeqi T, Pearson EG (2021) Enhanced recovery after surgery in children. Transl Gastroenterol Hepatol 6:46. https://doi.org/10.21037/tgh-20-188

    Article  PubMed  PubMed Central  Google Scholar 

  4. Akerman M, Pejcic N, Velickovic I (2018) A review of the quadratus lumborum block and ERAS. Front Med (Lausanne) 5:44. https://doi.org/10.3389/fmed.2018.00044

    Article  PubMed  Google Scholar 

  5. Chakraborty A, Goswami J, Patro V (2015) Ultrasound-guided continuous quadratus lumborum block for postoperative analgesia in a pediatric patient. A Case Rep 4:34–36. https://doi.org/10.1213/XAA.0000000000000090

    Article  Google Scholar 

  6. Ishio J, Komasawa N, Kido H et al (2017) Evaluation of ultrasound-guided posterior quadratus lumborum block for postoperative analgesia after laparoscopic gynecologic surgery. J Clin Anesth 41:1–4. https://doi.org/10.1016/j.jclinane.2017.05.015

    Article  PubMed  Google Scholar 

  7. Ipek CB, Kara D, Yilmaz S et al (2019) Comparison of ultrasound-guided transversus abdominis plane block, quadratus lumborum block, and caudal epidural block for perioperative analgesia in pediatric lower abdominal surgery. Turk J Med Sci 49:1395–1402. https://doi.org/10.3906/sag-1812-59

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Oksuz G, Arslan M, Urfalioglu A et al (2020) Comparison of quadratus lumborum block and caudal block for postoperative analgesia in pediatric patients undergoing inguinal hernia repair and orchiopexy surgeries: a randomized controlled trial. Reg Anesth Pain Med 45:187–191. https://doi.org/10.1136/rapm-2019-101027

    Article  PubMed  Google Scholar 

  9. Oksuz G, Bilal B, Gurkan Y et al (2017) Quadratus lumborum block versus transversus abdominis plane block in children undergoing low abdominal surgery: a randomized controlled trial. Reg Anesth Pain Med 42:674–679. https://doi.org/10.1097/AAP.0000000000000645

    Article  PubMed  Google Scholar 

  10. Zhao WL, Li SD, Wu B et al (2021) Quadratus lumborum block is an effective postoperative analgesic technique in pediatric patients undergoing lower abdominal surgery: a meta-analysis. Pain Phys 24:E555–E563

    Google Scholar 

  11. Elsharkawy H, El-Boghdadly K, Barrington M (2019) Quadratus lumborum block: anatomical concepts, mechanisms, and techniques. Anesthesiology 130:322–335. https://doi.org/10.1097/ALN.0000000000002524

    Article  PubMed  Google Scholar 

  12. Kashtan MA, Graham DA, Rangel SJ (2022) Utilization and performance benchmarking for postoperative imaging in children with complicated appendicitis: results from a multicenter collaborative Cohort Study. Ann Surg 275(4):816–823. https://doi.org/10.1097/SLA.0000000000004250

    Article  PubMed  Google Scholar 

  13. Ogrinc G, Davies L, Goodman D, et al. SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process. BMJ Qual Saf. 2016;25:986–92. https://doi.org/10.1136/bmjqs-2015-004411.

  14. Walter CM, Abbasian N, Olbrecht VA (2020) Trends in pediatric pain: thinking beyond opioids. Anesthesiol Clin 38:663–678. https://doi.org/10.1016/j.anclin.2020.04.002

    Article  PubMed  Google Scholar 

  15. Wolf AR (2012) Effects of regional analgesia on stress responses to pediatric surgery. Paediatr Anaesth 22(1):19–24

    Article  PubMed  Google Scholar 

  16. Furuya T, Kato J, Yamamoto Y, Hirose N, Suzuki T (2018) Comparison of dermatomal sensory block following ultrasound-guided transversus abdominis plane block by the lateral and posterior approaches: A randomized controlled trial. J Anaesthesiol Clin Pharmacol 34(2):205–210. https://doi.org/10.4103/joacp.JOACP_295_15

    Article  PubMed  PubMed Central  Google Scholar 

  17. Hammi C, Ahn K. Transversus Abdominis Plane Block. In: StatPearls. Treasure Island (FL): StatPearls Publishing; January 29, 2023.

  18. Verma K, Malawat A, Jethava D, Jethava DD (2019) Comparison of transversus abdominis plane block and quadratus lumborum block for post-caesarean section analgesia: A randomised clinical trial. Indian J Anaesth 63(10):820–826. https://doi.org/10.4103/ija.IJA_61_19

    Article  PubMed  PubMed Central  Google Scholar 

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Funding

No funding was received to complete this study.

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Authors and Affiliations

Authors

Contributions

L.B., K.S., and R.L. contributed to the conception and design of the research project. K.S., D.P., K.F., and B.B. contributed through data acquisition. S.J.M. and D.P. contributed through data analysis. All authors contributed to the interpretation of the data and its analysis. D.P. and S.J.M. contributed to the drafting of the manuscript and development of all figures. All authors critically revised the manuscript, agreed to be fully accountable for ensuring the integrity and accuracy of the work, and read and approved the final manuscript.

Corresponding author

Correspondence to Devon Pace.

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Pace, D., Mack, S.J., Sadacharam, K. et al. Implementation of a quadratus lumborum regional block protocol with assessment of effectiveness for patients with appendicitis: a quality improvement project. Pediatr Surg Int 39, 267 (2023). https://doi.org/10.1007/s00383-023-05522-x

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