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Polypoid disease of colon in children

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Abstract

Polyps in gastrointestinal tract are mostly benign and result from hamartomas or lymphoid hyperplasia of submucosa. They usually occur as isolated lesions in children and are referred to as juvenile polyps. Multiple polyps with inherited origin are called polyposis and can be seen as a part of the syndrome. The polyps with adenomatous histopathology have malignant potential and necessitate genetic testing and colonoscopy to define the risk of cancer. Although simple endoscopic removal is adequate in the treatment of juvenile polyps, children with familial adenomatous polyposis (FAP) need total colectomy with ileorectal anastomosis (IRA) or ileal pouch-anal anastomosis (IPAA). The timing of prophylactic colectomy and the type of surgical treatment are controversial in children. The clinical features, the assessment of cancer risk, and the alternatives of the surgical treatment of polyps are reviewed in this paper.

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Acknowledgements

The author would like to thank Associate Professor Semire Serin Ezer for sharing the first and fourth figures from her personal archive.

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  1. Department of Paediatric Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey

    Tutku Soyer

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Correspondence to Tutku Soyer.

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Soyer, T. Polypoid disease of colon in children. Pediatr Surg Int 36, 447–455 (2020). https://doi.org/10.1007/s00383-020-04621-3

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