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The prognostic factors and the outcome of primary isolated fetal ascites

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Abstract

Purpose

The purpose of the present study was to evaluate the prognostic factors and review the outcome of primary isolated fetal ascites.

Methods

A retrospective cohort study was conducted for fetuses with primary isolated ascites with a prenatal diagnosis between 1994 and 2009. The patients were divided into the favorable group (Group I) whose ascites were resolved by medical treatment alone and an unfavorable group (Group II) who required surgical intervention after birth due to refractory ascites.

Results

There were seven patients in Group I and five patients in Group II. Six of seven patients who developed ascites after 30 weeks’ gestation were categorized in Group I, and four of five infants who developed ascites before 30 weeks’ gestation were categorized in Group II. There was a negative correlation between the gestational age at diagnosis and the severity of the fetal abdominal distention. In Group II, the ascites resolved in two cases and was reaccommodated in another two cases after surgery. An infant with trisomy 21 received continuous drainage and eventually died of infection.

Conclusions

The prognosis of primary isolated fetal ascites can be predicted based on the gestational age at diagnosis and the severity of the fetal abdominal distention.

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References

  1. Machin GA (1989) Hydrops revisited: literature review of 1, 414 cases published in the 1980 s. Am J Med Genet 34:366–390. doi:10.1002/ajmg.1320340313

    Article  PubMed  CAS  Google Scholar 

  2. Yang JI, Kim HS, Chang KH, Hong J, Joo HJ, Ryu HS (2004) Intrauterine intussusception presenting as fetal ascites at prenatal ultrasonography. Am J Perinatol 21:241–246. doi:10.1055/s-2004-828607

    Article  PubMed  Google Scholar 

  3. Favre R, Dreux S, Dommergues M, Dumez Y, Luton D, Oury JF, Fiblec BL, Nisand I, Muller F (2004) Nonimmune fetal ascites: A series of 79 cases. Am J Obstet Gynecol 190:407–412. doi:10.1016/j.ajog.2003.09.016

    Article  PubMed  Google Scholar 

  4. Schmider A, Henrich W, Reles A, Kjos S, Dudenhausen JW (2003) Etiology and prognosis of fetal ascites. Fetal Diagn Ther 18:230–236. doi:10.1159/000070801

    Article  PubMed  Google Scholar 

  5. Chereau E, Lejeune V, Gonzales M, Carbonne B (2007) Voluminous fetal chylous ascites: a case of complete spontaneous prenatal regression. Fetal Diagn Ther 22:81–84. doi:10.1159/000097101

    Article  PubMed  Google Scholar 

  6. Sarno AP Jr, Bruner JP, Southgate WM (1990) Congenital chyloperitoneum as a cause of isolated fetal ascites. Obstet Gynecol 76:955–957

    PubMed  Google Scholar 

  7. Servelle M (1991) Congenital malformation of the lymphatics of the small intestine. J Cardiovasc Surg (Torino) 32:159–165

    CAS  Google Scholar 

  8. Kuroiwa M, Toki F, Suzuki M, Suzuki N (2007) Successful laparoscopic ligation of the lymphatic trunk for refractory chylous ascites. J Pediatr Surg 42:E15–E18. doi:10.1016/j.jpedsurg.2007.02.036

    Article  PubMed  Google Scholar 

  9. Mitsunaga T, Yoshida H, Iwai J, Matsunaga T, Kouchi K, Ohtsuka Y, Okada T, Hishiki T, Ohnuma N (2001) Successful surgical treatment of two cases of congenital chylous ascites. J Pediatr Surg 36:1717–1719. doi:10.1053/jpsu.2001.27973

    Article  PubMed  CAS  Google Scholar 

  10. Aalami OO, Allen DB, Organ CH Jr (2000) Chylous ascites: a collective review. Surgery 128:761–778. doi:10.1067/msy.2000.109502

    Article  PubMed  CAS  Google Scholar 

  11. Campisi C, Bellini C, Eretta C, Zilli A, da Rin E, Davini D, Bonioli E, Boccardo F (2006) Diagnosis and management of primary chylous ascites. J Vasc Surg 43:1244–1248. doi:10.1016/j.jvs.2005.11.064

    Article  PubMed  Google Scholar 

  12. te Pas AB, vd Ven K, Stokkel MP, Walther FJ (2004) Intractable congenital chylous ascites. Acta Paediatr 93:1403–1405

    Article  PubMed  CAS  Google Scholar 

  13. Richards DS, Wagman AJ, Cabaniss ML (1990) Ascites not due to congestive heart failure in a fetus with lupus-induced heart block. Obstet Gynecol 76:957–959

    PubMed  CAS  Google Scholar 

  14. Hecher K, Henning K, Spernol R, Szalay S (1991) Spontaneous remission of urinary tract obstruction and ascites in a fetus with posterior urethral valves. Ultrasound Obstet Gynecol 1:426–430. doi:10.1046/j.1469-0705.1991.01060426.x

    Article  PubMed  CAS  Google Scholar 

  15. De Russo PA, Benson J, Lau H (2003) Intestinal malrotation and omental cyst presenting as fetal ascites. J Pediatr Gastroenterol Nutr 36:283–286

    Article  Google Scholar 

  16. da Silva OP, Ramanan R, Romano W, Bocking A, Evans M (1996) Nonimmune hydrops fetalis, pulmonary sequestration, and favorable neonatal outcome. Obstet Gynecol 88:681–683

    Article  PubMed  CAS  Google Scholar 

  17. Maconochie IK, Chong S, Mieli-Vergani G, Lake BD, Mowat AP (1989) Fetal ascites: an unusual presentation of niemann-pick disease type c. Arch Dis Child 64:1391–1393

    Article  PubMed  CAS  Google Scholar 

  18. Bishry GE (2008) The outcome of isolated fetal ascites. Eur J Obstet Gynecol Reprod Biol 137:43–46. doi:10.1016/j.ejogrb.2007.05.007

    Article  PubMed  Google Scholar 

  19. Unger SW, Chandler JG (1983) Chylous ascites in infants and children. Surgery 93:455–461 (0039-6060(83)90223-4[pii])

    PubMed  CAS  Google Scholar 

  20. Noel AA, Gloviczki P, Bender CE, Whitley D, Stanson AW, Deschamps C (2001) Treatment of symptomatic primary chylous disorders. J Vasc Surg 34:785–791. doi:10.1067/mva.2001.118800

    Article  PubMed  CAS  Google Scholar 

  21. Willis RA (ed) (1962) The borderland of embryology and pathology, Second edition edn. Butterworths, London

    Google Scholar 

  22. Karagol BS, Zenciroglu A, Gokce S, Kundak AA, Ipek MS (2010) Therapeutic management of neonatal chylous ascites: report of a case and review of the literature. Acta Paediatr 99:1307–1310. doi:10.1111/j.1651-2227.2010.01818.x

    Article  PubMed  Google Scholar 

  23. Antao B, Croaker D, Squire R (2003) Successful management of congenital chyloperitoneum with fibrin glue. J Pediatr Surg 38:E7–E8 (S0022346803006018[pii])

    Article  PubMed  Google Scholar 

  24. Zeidan S, Delarue A, Rome A, Roquelaure B (2008) Fibrin glue application in the management of refractory chylous ascites in children. J Pediatr Gastroenterol Nutr 46:478–481. doi:10.1097/MPG.0b013e31815ce5be

    Article  PubMed  CAS  Google Scholar 

  25. Smeltzer DM, Stickler GB, Fleming RE (1986) Primary lymphatic dysplasia in children: chylothorax, chylous ascites, and generalized lymphatic dysplasia. Eur J Pediatr 145:286–292

    Article  PubMed  CAS  Google Scholar 

  26. Matsufuji H, Nishio T, Hosoya R (2006) Successful treatment for intractable chylous ascites in a child using a peritoneovenous shunt. Pediatr Surg Int 22:471–473. doi:10.1007/s00383-006-1648-1

    Article  PubMed  Google Scholar 

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Correspondence to Satoko Nose.

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Nose, S., Usui, N., Soh, H. et al. The prognostic factors and the outcome of primary isolated fetal ascites. Pediatr Surg Int 27, 799–804 (2011). https://doi.org/10.1007/s00383-011-2855-y

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  • DOI: https://doi.org/10.1007/s00383-011-2855-y

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