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A rare MRI finding of NF-1: perineural arachnoidal gliomatosis

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Abstract

Optic pathway gliomas are the most common central nervous system neoplasms in patients with neurofibromatosis type 1. Perineural arachnoidal gliomatosis is a rare and distinctive growth pattern of optic nerve glioma, in which the tumor infiltrates through the pia mater and pre-dominantly involves the subarachnoid space around the optic nerve. Here, we report an 8-year-old girl with perineural arachnoidal gliomatosis associated with neurofibromatosis type 1.

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Abbreviations

NF1:

Neurofibromatosis type 1

OPG:

Optic pathway gliomas

ONG:

Optic nerve gliomas

CSF:

Cerebrospinal fluid

FASI:

Focal areas of signal intensities

PAG:

Perineural arachnoidal gliomatosis

ONSM:

Optic nerve sheath meningioma

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Authors and Affiliations

  1. Division of Pediatric Radiology, Department of Radiology, Gazi University School of Medicine, 06560, Ankara, Turkey

    Merve Yazol, Betul Emine Derinkuyu & Oznur Boyunaga

Authors
  1. Merve Yazol
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  2. Betul Emine Derinkuyu
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  3. Oznur Boyunaga
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Contributions

Author Contributions Statement M.Y. and B.E.D. wrote the main manuscript text and M.Y. and B.E.D. prepared figures. All authors reviewed the manuscript.

Corresponding author

Correspondence to Merve Yazol.

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The authors declare no competing interests.

Ethical statement

Our institution’s committee on human research approved this study and informed consent was obtained from all individual participants included in the study.

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On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Yazol, M., Derinkuyu, B.E. & Boyunaga, O. A rare MRI finding of NF-1: perineural arachnoidal gliomatosis. Childs Nerv Syst 38, 1825–1828 (2022). https://doi.org/10.1007/s00381-022-05563-y

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  • DOI: https://doi.org/10.1007/s00381-022-05563-y

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