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Posterior fossa syndrome with delayed MR evidence of unilateral superior cerebellar peduncle (SCP) damage

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Abstract

Posterior fossa syndrome (PFS) is a well-known sequela of midline posterior fossa tumor resection. Patients typically exhibit transient behavioral, motor, and oculomotor disturbances that resolve within a few weeks to several months after surgery. The underlying pathophysiology of PFS is not completely understood, but contemporary literature has implicated injury to the dentate nucleus and/or exiting dentatothalamocortical fiber bundles as a causative factor. The authors present a case of a young male who developed a delayed variant of PFS typified by motor deficits and demonstrated diffusion restriction in the ipsilateral superior cerebellar peduncle. Because the correlation between PFS and the superior cerebellar peduncle injury is poorly described in the literature, particularly with regard to relevant radiographic imaging, the authors of this report hope their findings will contribute to that insufficient body of evidence.

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Abbreviations

SCP:

superior cerebellar peduncle

pECP:

proximal efferent cerebellar pathways

DTI:

diffusion tensor imaging

PFS:

posterior fossa syndrome

CMS:

cerebellar mutism syndrome

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Authors and Affiliations

  1. Department of Neurosurgery, University of Texas Health Science Center at San Antonio, 7709 Floyd Curl Drive, Mail Code 7843, Medical School Building 102F, San Antonio, TX, 78229-3900, USA

    Kevin Carr & Izabela Tarasiewicz

  2. School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Pegah Ghamasaee

  3. Department of Neuroradiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Achint Singh

Authors
  1. Kevin Carr
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  2. Pegah Ghamasaee
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  3. Achint Singh
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  4. Izabela Tarasiewicz
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Correspondence to Kevin Carr.

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No financial support was obtained for this manuscript. The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

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Carr, K., Ghamasaee, P., Singh, A. et al. Posterior fossa syndrome with delayed MR evidence of unilateral superior cerebellar peduncle (SCP) damage. Childs Nerv Syst 33, 503–507 (2017). https://doi.org/10.1007/s00381-016-3287-8

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  • DOI: https://doi.org/10.1007/s00381-016-3287-8

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