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Prognostic value of pulmonary oedema assessed by lung ultrasound in patient with acute heart failure

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A Correction to this article was published on 11 December 2020

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Abstract

It is very important to assess pulmonary oedema in patients with acute heart failure. The aim of the study was to investigate the accuracy of lung ultrasound in evaluating pulmonary oedema and to explore lung ultrasound in predicting the prognosis. One hundred twenty-four acute heart failure patients were divided into 3 groups, according to the total number of lung ultrasound B-lines groups: B-lines < 15 was the mild pulmonary oedema group (33 cases), 15 ≤ B-lines < 30 was the moderate pulmonary oedema group (33 cases), and B-lines ≥ 30 was the severe pulmonary oedema group (58 cases). The PiCCO monitoring system was used in 11 patients and measured 26 times in different clinical situations. EVLWI have a higher positive correlation with B-lines (r = 0.95), compared with NT-proBNP and E/e′ (r = 0.72, r = 0.62). During 1 year of follow-up, a multivariate cox regression analysis showed that age, E/e′ and B-lines ≥ 30 at admission (C-index of 75%) were risk factors for prognosis. 12-month event-free survival showed a significantly worse outcome was observed in patients with ≥ 30 B-lines at admission. B-lines have a good correlation with EVLWI; age, E/e′ and B-lines ≥ 30 at admission were risk factors for prognosis.

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Data availability

The datasets during and/or analyzed during this study are available from the corresponding author on reasonable request.

Change history

Abbreviations

PiCCO:

Pulse indicator continuous cardiac output

EVLW:

Extravascular lung water

NT-proBNP:

N-terminal pro brain natriuretic peptide

EVLWI:

Extravascular lung water index

NYHA:

New York Heart Association

EF:

Ejection fraction

LVESD:

Left ventricular end-systolic diameter

LVEDD:

Left ventricular end-diastolic diameter

PAP:

Pulmonary arterial pressure

IVC:

Inferior vena cava diameter

ROC:

Receiver operating characteristic

AUC:

Area under the curve

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Funding

Clinical Research Support Fund of Chinese PLA General Hospital, Grant no [2018FC-304M-CXYY-01].

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Authors and Affiliations

  1. Department of Cardiology, Fourth Medical Center of Chinese, PLA General Hospital, Beijing, 100048, China

    Feifei Yang, Qiushuang Wang, Liwei Zhang, Yongjiang Ma & Qiang Chen

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  1. Feifei Yang
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Contributions

FY and QW participated in the design of the study and performed the ultrasound examinations and analyzed the data. LZ, DH and DS participated in the design of the study and helped to draft the manuscript. YW, YM and QC performed the statistical analysis and helped to draft the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Feifei Yang.

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Conflict of interest

The authors have no conflict of interest.

Ethical approval and consent to participate

This study was approved by the ethics committee of the Fourth Medical Center of Chinese PLA General Hospital, and written informed consent was provided by all the subjects.

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Feifei Yang and Qiushuang Wang are the first authors.

The original online version of this article was revised due to the article note was missed and included in this version. In addition, Table 4 contain error in the previous online version and corrected in this version.

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Yang, F., Wang, Q., Zhang, L. et al. Prognostic value of pulmonary oedema assessed by lung ultrasound in patient with acute heart failure. Heart Vessels 36, 518–527 (2021). https://doi.org/10.1007/s00380-020-01719-5

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  • DOI: https://doi.org/10.1007/s00380-020-01719-5

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